214205

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/-
Location 189131..189801 Replicon chromosome
Accession NZ_CP082141
Organism Erwinia persicina strain Cp2

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag K6L24_RS22255 Protein ID WP_245006705.1
Coordinates 189463..189801 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag K6L24_RS00810 Protein ID WP_062748154.1
Coordinates 189131..189445 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6L24_RS00785 (K6L24_00785) 184550..185458 - 909 WP_062749615.1 LysR family transcriptional regulator -
K6L24_RS00790 (K6L24_00790) 185589..186230 + 642 WP_118665260.1 hydrolase -
K6L24_RS00795 (K6L24_00795) 186270..186854 + 585 WP_062748150.1 antibiotic biosynthesis monooxygenase -
K6L24_RS00800 (K6L24_00800) 186844..188715 + 1872 WP_187510283.1 amidohydrolase -
K6L24_RS22250 188820..189146 + 327 WP_245006704.1 helix-turn-helix transcriptional regulator -
K6L24_RS00810 (K6L24_00810) 189131..189445 + 315 WP_062748154.1 HipA N-terminal domain-containing protein Antitoxin
K6L24_RS22255 189463..189801 + 339 WP_245006705.1 HipA domain-containing protein Toxin
K6L24_RS22260 189743..190123 + 381 WP_240343549.1 hypothetical protein -
K6L24_RS00820 (K6L24_00820) 190141..191001 - 861 WP_162901003.1 hypothetical protein -
K6L24_RS00825 (K6L24_00825) 191025..192002 - 978 WP_222681855.1 hypothetical protein -
K6L24_RS00830 (K6L24_00830) 192185..193105 + 921 WP_240343550.1 substrate-binding domain-containing protein -
K6L24_RS00835 (K6L24_00835) 193724..194419 + 696 WP_245006706.1 common pilus major fimbrillin subunit EcpA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12331.20 Da        Isoelectric Point: 7.9893

>T214205 WP_245006705.1 NZ_CP082141:189463-189801 [Erwinia persicina]
MTPLKSERERALGYATKGLKMLTGLARVEPQLTFTRAQFVQYLPKEQQGMSISGYQPKLQMVMEDGAFAVVESKGNYILK
PSPVDFPQLAENEHDADGAAGIRCTATRPVTL

Download         Length: 339 bp

>T214205 NZ_CP110015:c2178478-2178224 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12184.96 Da        Isoelectric Point: 8.4054

>AT214205 WP_062748154.1 NZ_CP082141:189131-189445 [Erwinia persicina]
MRRRLTVWLYGEPVGWLTQNDEGYLFEYRPDYAGPPLSLSLPVDKKRFPRNTLHPYFASLAPEGWLKRRYSQLQKIDEQD
LLGMLLHNGENLIGAVRLSVEEPR

Download         Length: 315 bp

>AT214205 NZ_CP110015:c2178726-2178475 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References