Detailed information of TA system TA021395

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 4752692..4753281
• Replicon: chromosome
• Accession: NC_007705
• Organism: Xanthomonas oryzae pv. oryzae MAFF 311018

Toxin (Protein)

• Gene name: graT
• Uniprot ID: A0A8E2YMU3
• Locus tag: TX61_RS22115
• Protein ID: WP_011260747.1
• Coordinates: 4753000..4753281 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: TX61_RS22110
• Protein ID: WP_011260746.1
• Coordinates: 4752692..4752982 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TX61_RS22080	4747975..4748448	-	474	Protein_4267	DUF4123 domain-containing protein	-
TX61_RS22085	4748451..4748885	-	435	WP_011409747.1	PAAR domain-containing protein	-
TX61_RS22090	4749001..4749245	-	245	Protein_4269	hypothetical protein	-
TX61_RS22100	4749581..4749913	+	333	WP_011260743.1	hypothetical protein	-
TX61_RS22105	4750363..4751754	-	1392	WP_011409748.1	nucleoside hydrolase	-
TX61_RS22110	4752692..4752982	-	291	WP_011260746.1	HigA family addiction module antidote protein	Antitoxin
TX61_RS22115	4753000..4753281	-	282	WP_011260747.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
TX61_RS22120	4753376..4755628	-	2253	WP_011409750.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (4-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11070.83 Da
• Isoelectric Point: 10.2139

>T21395 WP_011260747.1 NC_007705:c4753281-4753000 [Xanthomonas oryzae pv. oryzae MAFF 311018]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Nucleotide

• Length: 282 bp

>T21395 NC_007705:c4753281-4753000 [Xanthomonas oryzae pv. oryzae MAFF 311018]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCAGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10420.07 Da
• Isoelectric Point: 7.2040

>AT21395 WP_011260746.1 NC_007705:c4752982-4752692 [Xanthomonas oryzae pv. oryzae MAFF 311018]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT21395 NC_007705:c4752982-4752692 [Xanthomonas oryzae pv. oryzae MAFF 311018]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA