Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 3927650..3928218 Replicon chromosome
Accession NC_007643
Organism Rhodospirillum rubrum ATCC 11170

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag RRU_RS17625 Protein ID WP_164922597.1
Coordinates 3927650..3927928 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag RRU_RS17630 Protein ID WP_011391158.1
Coordinates 3927925..3928218 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RRU_RS17605 3922927..3923775 + 849 WP_011391153.1 S-formylglutathione hydrolase -
RRU_RS17610 3924018..3925232 + 1215 WP_011391154.1 6-phosphofructokinase -
RRU_RS17615 3925222..3926280 - 1059 WP_011391155.1 glycosyltransferase family 2 protein -
RRU_RS17620 3926470..3927348 + 879 WP_011391156.1 hypothetical protein -
RRU_RS17625 3927650..3927928 + 279 WP_164922597.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RRU_RS17630 3927925..3928218 + 294 WP_011391158.1 helix-turn-helix domain-containing protein Antitoxin
RRU_RS17635 3928377..3929606 - 1230 WP_011391159.1 amidohydrolase family protein -
RRU_RS17640 3929649..3930350 - 702 WP_011391160.1 ATP-binding cassette domain-containing protein -
RRU_RS17645 3930347..3931114 - 768 WP_011391161.1 ABC transporter ATP-binding protein -
RRU_RS17650 3931111..3931998 - 888 WP_011391162.1 branched-chain amino acid ABC transporter permease -
RRU_RS17655 3932020..3932892 - 873 WP_011391163.1 branched-chain amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(2-86)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-87)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10368.45 Da        Isoelectric Point: 11.4328

>T21384 WP_164922597.1 NC_007643:3927650-3927928 [Rhodospirillum rubrum ATCC 11170]
MLPADQRARFVWIATLLREAGPQKVREPYVKPLGGKLWEMRMKGKDGIARAIYLAAIGKRLVVVHVFVKKTQKTPRAALE
TAMRRAEEAGLL

Download         Length: 279 bp

>T21384 NC_007643:3927650-3927928 [Rhodospirillum rubrum ATCC 11170]
ATGTTGCCCGCTGATCAGAGGGCGCGGTTCGTCTGGATCGCGACTCTCTTGCGCGAGGCCGGTCCCCAGAAAGTTCGAGA
GCCCTATGTAAAGCCATTGGGTGGAAAGCTTTGGGAGATGCGGATGAAAGGCAAGGATGGGATCGCCCGCGCGATCTATC
TTGCCGCGATCGGCAAACGGTTGGTCGTCGTGCATGTCTTTGTGAAGAAAACCCAGAAGACACCGCGCGCGGCGCTTGAA
ACCGCCATGCGCCGGGCCGAGGAAGCCGGACTGCTATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10642.98 Da        Isoelectric Point: 6.7268

>AT21384 WP_011391158.1 NC_007643:3927925-3928218 [Rhodospirillum rubrum ATCC 11170]
MTDIDTLHQEWSQDPAYRAAHEELRPEFELATALIAARARAGLSQAELAERMGTTQSAIARLEGGRHWPSRRTLERLAAA
TGTRVVFKLVDSAGTAI

Download         Length: 294 bp

>AT21384 NC_007643:3927925-3928218 [Rhodospirillum rubrum ATCC 11170]
ATGACCGATATTGACACATTGCACCAGGAATGGAGCCAAGACCCGGCCTATCGGGCGGCCCATGAAGAGCTGCGCCCCGA
GTTCGAACTGGCGACCGCCTTGATCGCGGCGCGAGCCCGGGCGGGTTTGTCCCAGGCGGAACTGGCCGAGCGCATGGGAA
CGACGCAAAGCGCCATCGCCCGCCTGGAAGGCGGCCGCCACTGGCCCAGCCGGCGCACCCTGGAACGCCTTGCCGCGGCG
ACGGGAACCCGCGTCGTTTTCAAGCTGGTCGACTCCGCCGGGACCGCCATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References