21367

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2443914..2444098 Replicon chromosome
Accession NC_007622
Organism Staphylococcus aureus RF122

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag SAB_RS12495 Protein ID WP_000482649.1
Coordinates 2443991..2444098 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2443914..2443974 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAB_RS12470 2439529..2439696 - 168 WP_001798790.1 hypothetical protein -
SAB_RS12480 2439927..2441638 - 1712 Protein_2359 ABC transporter ATP-binding protein -
SAB_RS12485 2441663..2443426 - 1764 Protein_2360 ABC transporter ATP-binding protein -
- 2443914..2443974 + 61 - - Antitoxin
SAB_RS12495 2443991..2444098 - 108 WP_000482649.1 type I toxin-antitoxin system Fst family toxin Toxin
SAB_RS12500 2444233..2444619 - 387 WP_000779353.1 flippase GtxA -
SAB_RS12505 2444887..2446029 + 1143 WP_001176861.1 glycerate kinase -
SAB_RS12510 2446089..2446748 + 660 WP_000831304.1 hypothetical protein -
SAB_RS12515 2446931..2448142 + 1212 WP_001191925.1 multidrug effflux MFS transporter -
SAB_RS12520 2448265..2448738 - 474 WP_000456485.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3958.73 Da        Isoelectric Point: 9.5674

>T21367 WP_000482649.1 NC_007622:c2444098-2443991 [Staphylococcus aureus RF122]
MFNLLINIMTSAISGCLVAFFAHWLRTCNNKKGDK

Download         Length: 108 bp

>T21367 NC_007622:c2444098-2443991 [Staphylococcus aureus RF122]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GTGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT21367 NC_007622:2443914-2443974 [Staphylococcus aureus RF122]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTATTGCCGTAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References