Detailed information of TA system TA021360

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG2-SprA2AS/-
• Location: 973064..973281
• Replicon: chromosome
• Accession: NC_007622
• Organism: Staphylococcus aureus RF122

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: SAB_RS04795
• Protein ID: WP_000623369.1
• Coordinates: 973064..973171 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	973166..973281 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAB_RS04770	969737..970306	-	570	WP_000283455.1	competence protein ComK	-
SAB_RS04775	970516..970734	+	219	WP_000876826.1	IDEAL domain-containing protein	-
SAB_RS04780	970815..971801	-	987	WP_000668820.1	lipoate--protein ligase	-
SAB_RS04785	972000..972176	+	177	WP_000214898.1	YkvS family protein	-
SAB_RS04790	972191..972793	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
SAB_RS04795	973064..973171	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	973166..973281	-	116	-	-	Antitoxin
SAB_RS04800	973710..973811	+	102	WP_042852647.1	hypothetical protein	-
SAB_RS14385	973821..974093	+	273	WP_078062708.1	lactococcin 972 family bacteriocin	-
SAB_RS04805	974136..976100	+	1965	WP_000870792.1	bacteriocin-associated integral membrane family protein	-
SAB_RS04810	976103..976426	+	324	WP_000668625.1	YxeA family protein	-
SAB_RS04815	976423..977061	+	639	WP_042852651.1	ABC transporter ATP-binding protein	-
SAB_RS14390	977149..977439	-	291	WP_001795266.1	hypothetical protein	-
SAB_RS04825	977772..978059	+	288	WP_000410749.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T21360 WP_000623369.1 NC_007622:973064-973171 [Staphylococcus aureus RF122]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T21360 NC_007622:973064-973171 [Staphylococcus aureus RF122]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 116 bp

>AT21360 NC_007622:c973281-973166 [Staphylococcus aureus RF122]
GTAAAAAGACGACATGCAGGAACATGTCGCCAAATGAGCCCGTTAAAAAGACGGTGACTAAATGAGATTTTCTTTAACCA
TCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin