Detailed information of TA system TA213567

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 1035631..1036133
• Replicon: chromosome
• Accession: NZ_CP081864
• Organism: Symbiopectobacterium purcellii strain SyEd1

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: K6K13_RS04895
• Protein ID: WP_222159781.1
• Coordinates: 1035631..1035885 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: K6K13_RS04900
• Protein ID: WP_195316128.1
• Coordinates: 1035882..1036133 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K6K13_RS04885 (K6K13_04885)	1030809..1031642	-	834	WP_222159780.1	glyoxylate bypass operon transcriptional repressor IclR	-
K6K13_RS04890 (K6K13_04890)	1031848..1035555	+	3708	WP_252120422.1	methionine synthase	-
K6K13_RS04895 (K6K13_04895)	1035631..1035885	-	255	WP_222159781.1	Txe/YoeB family addiction module toxin	Toxin
K6K13_RS04900 (K6K13_04900)	1035882..1036133	-	252	WP_195316128.1	YoeB-YefM toxin-antitoxin system antitoxin YefM	Antitoxin
K6K13_RS04905 (K6K13_04905)	1036309..1037232	+	924	WP_222157526.1	IS5 family transposase	-
K6K13_RS04910 (K6K13_04910)	1037649..1038644	+	996	WP_252120423.1	AraC family transcriptional regulator	-
K6K13_RS04915 (K6K13_04915)	1038793..1040916	+	2124	WP_222159782.1	TonB-dependent siderophore receptor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1036309..1037232	923

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9986.43 Da
• Isoelectric Point: 8.0367

>T213567 WP_222159781.1 NZ_CP081864:c1035885-1035631 [Symbiopectobacterium purcellii]
MKSTWSEEAWEDYLYWQDTDNRMVKKINALIKDVLRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAIAEGAILIAAC
RYHY

Nucleotide

• Length: 255 bp

>T213567 NZ_CP109692:c958047-957547 [Enterobacter asburiae]
ATGTTATCAGAGGGAACCGATTATGACTTCGAGGATTTTGATTGTGGCGAACCCTCGCTAAATGCCTTCCTTGCTGAACA
TCTGGTGCGTCAGCACAATGGGCGTATTTTACGAGCCTACCTGCTTAAAGAGCGCGATCGTCCGCGAGTCCTGGGTTATT
ACACTTTATCGGGAAGCTGTTTTGAAAGAGCGATGCTTCCTTCTAAGACTCAGCAGCGCCGAATCCCTTATATCAACGTA
CCCAGCGTGACGCTGGGACGTCTGGCTGTAGATAAAACACTACAGGGAAACGAGTGGGGAACAACGCTCGTTGCGCATGC
TATGCGCGTTGTCTACCTGGCTTCACAGGCTGTGGGGGTACACGGAATATTTGTTGATGCCCTTAACGAGCGGGCAAAAC
GATTTTATCTGAAGCAGGGCTTTATCCCGCTGACAGCTGAAAACAGCCATTCTTTGTTCTTCCCTACAAAATCTATCGAA
CGGCTGTTTGAGCAAGAGTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9233.54 Da
• Isoelectric Point: 4.7946

>AT213567 WP_195316128.1 NZ_CP081864:c1036133-1035882 [Symbiopectobacterium purcellii]
MRTISYSEARQNLSATMMKTVEDHAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNAIESLKAGEGTEKG
IIE

Nucleotide

• Length: 252 bp

>AT213567 NZ_CP109692:c958344-958075 [Enterobacter asburiae]
ATGCCAGCACTTAAAAAACAGCGTATCGATCTTCGCTTAACGGACGAAGACAAAACAATGATTGAAGAAGCGGCGGCGAT
GACGAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGTGCTGCAGAGGTCATTGAGCAGCACCGTCGTC
TCGTATTAAACGAAGCATCATGGAATGCGGTGATGGATGCCATCGACAATCCGCCTGAGCCAAATGAACGCCTGAAACGA
GCAGCAAAACGGCTTCGAAACATGGAGTGA