Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2511678..2512455 Replicon chromosome
Accession NC_007614
Organism Nitrosospira multiformis ATCC 25196

Toxin (Protein)


Gene name mqsR Uniprot ID Q2Y6X0
Locus tag NMUL_RS11530 Protein ID WP_011381507.1
Coordinates 2511678..2511980 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag NMUL_RS11535 Protein ID WP_011381508.1
Coordinates 2511982..2512455 (+) Length 158 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMUL_RS15020 2506892..2509678 - 2787 WP_049783118.1 PAS domain S-box protein -
NMUL_RS11525 2509828..2510871 + 1044 WP_011380592.1 IS481 family transposase -
NMUL_RS11530 2511678..2511980 + 303 WP_011381507.1 type II toxin-antitoxin system MqsR family toxin Toxin
NMUL_RS11535 2511982..2512455 + 474 WP_011381508.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NMUL_RS11540 2512467..2512964 + 498 WP_011381509.1 type II toxin-antitoxin system MqsA family antitoxin -
NMUL_RS11545 2513126..2513491 - 366 WP_167535587.1 DUF1493 family protein -
NMUL_RS11550 2513497..2514114 - 618 WP_041352582.1 RHS repeat-associated core domain-containing protein -
NMUL_RS16215 2514139..2514276 - 138 WP_011381512.1 hypothetical protein -
NMUL_RS11560 2514979..2515674 + 696 WP_011381513.1 Bax inhibitor-1/YccA family protein -
NMUL_RS11565 2515783..2517102 - 1320 WP_011381514.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2509828..2510871 1043


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-99)

Antitoxin

(3-133)


Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11645.42 Da        Isoelectric Point: 9.9792

>T21356 WP_011381507.1 NC_007614:2511678-2511980 [Nitrosospira multiformis ATCC 25196]
MDKSKPHYELDKVKSLIRAGQYRITRVASEGGDKLGFKNTQEIAEFVLTLKRTDFYKSMTSNMNHKEWQDVYHGDGPTKK
VVYLKFIVTNDVLILSFKEK

Download         Length: 303 bp

>T21356 NC_007614:2511678-2511980 [Nitrosospira multiformis ATCC 25196]
ATGGACAAGAGCAAACCACATTACGAACTGGACAAGGTCAAAAGCTTAATACGCGCTGGTCAGTATCGGATAACAAGAGT
CGCAAGCGAAGGCGGCGACAAGCTAGGTTTTAAAAACACCCAAGAGATCGCGGAATTCGTGCTAACGCTGAAACGCACCG
ATTTCTATAAAAGCATGACAAGCAACATGAACCACAAGGAATGGCAAGACGTGTATCACGGCGACGGGCCAACGAAAAAA
GTGGTTTACCTGAAATTCATTGTCACGAACGACGTATTGATACTTTCCTTTAAGGAGAAATGA

Antitoxin


Download         Length: 158 a.a.        Molecular weight: 17964.30 Da        Isoelectric Point: 7.0860

>AT21356 WP_011381508.1 NC_007614:2511982-2512455 [Nitrosospira multiformis ATCC 25196]
MRCSLCGKGEVVAGTRDVPFTYKGQKTFIKNIRGEYCNRCGEGYYGPEHDGDILMAGYREFREKVDTVLAEQATFVEQVR
KKLGLDQREAGEIFGGGVNAFSRYETGKVRTPVSVMQLFTLLDRHPELLEEIRQNRYRTRGTQELREEVSAQKELTD

Download         Length: 474 bp

>AT21356 NC_007614:2511982-2512455 [Nitrosospira multiformis ATCC 25196]
ATGAGATGTTCACTGTGCGGGAAGGGCGAGGTGGTAGCGGGTACCCGCGATGTGCCCTTTACCTATAAGGGCCAAAAAAC
CTTTATTAAAAATATTCGGGGGGAGTACTGCAACCGCTGCGGCGAGGGTTACTATGGCCCGGAGCACGATGGCGATATTC
TCATGGCCGGATACCGCGAGTTCAGAGAAAAAGTCGATACTGTGCTGGCCGAGCAGGCCACATTCGTGGAGCAGGTGCGG
AAGAAACTGGGGCTCGACCAGCGTGAAGCAGGGGAGATTTTTGGCGGCGGAGTGAATGCCTTTTCGCGTTATGAGACTGG
AAAAGTCAGAACACCGGTCTCTGTCATGCAGCTGTTCACGCTACTCGACCGGCACCCTGAGCTACTTGAGGAAATCAGGC
AGAATAGATATCGGACCAGGGGTACACAGGAGCTTCGTGAGGAAGTATCCGCGCAGAAGGAACTGACGGATTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB Q2Y6X0


Antitoxin

Source ID Structure

References