Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 186429..186651 Replicon chromosome
Accession NZ_CP081706
Organism Escherichia coli strain AH04

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag J6O21_RS00890 Protein ID WP_001295224.1
Coordinates 186544..186651 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 186429..186486 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6O21_RS00870 182300..183283 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
J6O21_RS00875 183280..184284 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
J6O21_RS00880 184314..185585 - 1272 WP_001295225.1 aromatic amino acid transport family protein -
J6O21_RS00885 186061..186168 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
- 186429..186486 - 58 - - Antitoxin
J6O21_RS00890 186544..186651 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
J6O21_RS00895 187027..187134 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
J6O21_RS00900 187510..187617 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
J6O21_RS00905 187704..189383 - 1680 WP_000191613.1 cellulose biosynthesis protein BcsG -
J6O21_RS00910 189380..189571 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
J6O21_RS00915 189568..190590 - 1023 Protein_180 cellulose biosynthesis protein BcsE -
J6O21_RS00920 190646..191343 + 698 WP_094096600.1 IS1-like element IS1A family transposase -
J6O21_RS00925 191360..191482 + 123 Protein_182 cellulose biosynthesis protein BcsR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T213120 WP_001295224.1 NZ_CP081706:186544-186651 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T213120 NZ_CP107463:4176359-4176577 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 58 bp

>AT213120 NZ_CP081706:c186486-186429 [Escherichia coli]
CAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References