Detailed information of TA system TA212938

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 332398..332592
• Replicon: chromosome
• Accession: NZ_CP081505
• Organism: Enterococcus faecalis strain E006xJH2-2-TC1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: K4752_RS01685
• Protein ID: WP_015543884.1
• Coordinates: 332497..332592 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	332398..332462 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K4752_RS01670	328016..329758	+	1743	WP_002385355.1	PTS transporter subunit EIIC	-
K4752_RS01675	329749..331782	+	2034	WP_002361171.1	PRD domain-containing protein	-
K4752_RS01680	331793..332227	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	332398..332462	+	65	-	-	Antitoxin
K4752_RS01685	332497..332592	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
K4752_RS01690	332838..334610	+	1773	WP_002387897.1	PTS mannitol-specific transporter subunit IIBC	-
K4752_RS01695	334625..335062	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
K4752_RS01700	335077..336231	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
K4752_RS01705	336298..337413	-	1116	WP_002380024.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T212938 WP_015543884.1 NZ_CP081505:c332592-332497 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T212938 NZ_CP107408:c4845739-4845206 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT212938 NZ_CP081505:332398-332462 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin