Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2341304..2341958 Replicon chromosome
Accession NZ_CP081490
Organism Pseudomonas protegens strain PS1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag K5F93_RS10865 Protein ID WP_019092839.1
Coordinates 2341608..2341958 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag K5F93_RS10860 Protein ID WP_102864712.1
Coordinates 2341304..2341621 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5F93_RS10840 (K5F93_10840) 2336607..2337359 - 753 WP_221811555.1 UDP-2,3-diacylglucosamine diphosphatase -
K5F93_RS10845 (K5F93_10845) 2337356..2337859 - 504 WP_016965727.1 peptidylprolyl isomerase -
K5F93_RS10850 (K5F93_10850) 2338130..2339830 + 1701 WP_221811556.1 glutamine--tRNA ligase/YqeY domain fusion protein -
K5F93_RS10855 (K5F93_10855) 2339849..2341231 + 1383 WP_221811557.1 cysteine--tRNA ligase -
K5F93_RS10860 (K5F93_10860) 2341304..2341621 - 318 WP_102864712.1 transcriptional regulator Antitoxin
K5F93_RS10865 (K5F93_10865) 2341608..2341958 - 351 WP_019092839.1 hypothetical protein Toxin
K5F93_RS10870 (K5F93_10870) 2342196..2343659 - 1464 WP_015636299.1 NADH-quinone oxidoreductase subunit NuoN -
K5F93_RS10875 (K5F93_10875) 2343667..2345199 - 1533 WP_011062195.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13980.08 Da        Isoelectric Point: 8.9805

>T212929 WP_019092839.1 NZ_CP081490:c2341958-2341608 [Pseudomonas protegens]
MNALFIELPAFARYRKDFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFVDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T212929 NZ_CP107404:c91481-91065 [Klebsiella pneumoniae]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12086.93 Da        Isoelectric Point: 10.4439

>AT212929 WP_102864712.1 NZ_CP081490:c2341621-2341304 [Pseudomonas protegens]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITATEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATP
NAQATTLMRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT212929 NZ_CP107404:c91708-91478 [Klebsiella pneumoniae]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References