Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HTH(antitoxin) |
Location | 1749351..1749988 | Replicon | chromosome |
Accession | NZ_CP081457 | ||
Organism | Pseudomonas syringae pv. actinidifoliorum ICMP 18803 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | A237_RS07960 | Protein ID | WP_017700479.1 |
Coordinates | 1749674..1749988 (-) | Length | 105 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | A237_RS07955 | Protein ID | WP_017703368.1 |
Coordinates | 1749351..1749674 (-) | Length | 108 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A237_RS07930 (A237_007905) | 1745205..1745897 | - | 693 | WP_020341701.1 | tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO | - |
A237_RS07935 (A237_007910) | 1745911..1746372 | - | 462 | WP_004397572.1 | DUF1456 family protein | - |
A237_RS07940 (A237_007915) | 1746454..1747164 | - | 711 | WP_004397570.1 | rRNA pseudouridine synthase | - |
A237_RS07945 (A237_007920) | 1747258..1747698 | - | 441 | WP_005736177.1 | GNAT family N-acetyltransferase | - |
A237_RS07950 (A237_007925) | 1747800..1749143 | - | 1344 | WP_004397566.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
A237_RS07955 (A237_007930) | 1749351..1749674 | - | 324 | WP_017703368.1 | helix-turn-helix domain-containing protein | Antitoxin |
A237_RS07960 (A237_007935) | 1749674..1749988 | - | 315 | WP_017700479.1 | transcription elongation factor GreB | Toxin |
A237_RS07965 (A237_007940) | 1750117..1751205 | - | 1089 | WP_017700480.1 | catalase family protein | - |
A237_RS07970 (A237_007945) | 1751527..1753422 | + | 1896 | WP_005736172.1 | potassium transporter Kup | - |
A237_RS07975 (A237_007950) | 1753517..1754851 | - | 1335 | WP_017700481.1 | AcvB/VirJ family lysyl-phosphatidylglycerol hydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 105 a.a. Molecular weight: 11914.77 Da Isoelectric Point: 10.2260
>T212878 WP_017700479.1 NZ_CP081457:c1749988-1749674 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MIFIETPVFSSDLKNHLDDEEYRSLQVHLAEHPKSGALIEDTGGLRKIRWAAHGKGKSGGVRVIYYHVSAHYQIRMILIY
RKGILDSLTDKQKAQLRALNKGWK
MIFIETPVFSSDLKNHLDDEEYRSLQVHLAEHPKSGALIEDTGGLRKIRWAAHGKGKSGGVRVIYYHVSAHYQIRMILIY
RKGILDSLTDKQKAQLRALNKGWK
Download Length: 315 bp
>T212878 NZ_CP107390:2804646-2805029 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA
Antitoxin
Download Length: 108 a.a. Molecular weight: 12175.80 Da Isoelectric Point: 8.8041
>AT212878 WP_017703368.1 NZ_CP081457:c1749674-1749351 [Pseudomonas syringae pv. actinidifoliorum ICMP 18803]
MEKNLFDRLVESMTQMDEIDRGERQPSREFHIDAVQVKKIRQATGLSQVKFAKRIDVAVGTLRNWEQGRREPEGPARALL
RAIHNDPKHVLAALSSNGEELSETGRL
MEKNLFDRLVESMTQMDEIDRGERQPSREFHIDAVQVKKIRQATGLSQVKFAKRIDVAVGTLRNWEQGRREPEGPARALL
RAIHNDPKHVLAALSSNGEELSETGRL
Download Length: 324 bp
>AT212878 NZ_CP107390:2804404-2804646 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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