Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4150043..4150743 Replicon chromosome
Accession NZ_CP081016
Organism Pseudomonas sp. 2hn

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag K2O50_RS18670 Protein ID WP_050704792.1
Coordinates 4150447..4150743 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A923JZT3
Locus tag K2O50_RS18665 Protein ID WP_050704793.1
Coordinates 4150043..4150444 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K2O50_RS18650 (K2O50_18650) 4145219..4145968 - 750 WP_028692905.1 electron transfer flavoprotein subunit beta/FixA family protein -
K2O50_RS18655 (K2O50_18655) 4146511..4148175 + 1665 WP_050704795.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
K2O50_RS18660 (K2O50_18660) 4148244..4149893 - 1650 WP_050704794.1 hypothetical protein -
K2O50_RS18665 (K2O50_18665) 4150043..4150444 - 402 WP_050704793.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
K2O50_RS18670 (K2O50_18670) 4150447..4150743 - 297 WP_050704792.1 type II toxin-antitoxin system MqsR family toxin Toxin
K2O50_RS18675 (K2O50_18675) 4150838..4152163 - 1326 WP_050704791.1 MFS transporter -
K2O50_RS18680 (K2O50_18680) 4152217..4152702 - 486 WP_050704790.1 hypothetical protein -
K2O50_RS18685 (K2O50_18685) 4152874..4153350 - 477 WP_050704789.1 sigma-70 family RNA polymerase sigma factor -
K2O50_RS18690 (K2O50_18690) 4153566..4154744 + 1179 WP_050704788.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11205.11 Da        Isoelectric Point: 8.8385

>T212591 WP_050704792.1 NZ_CP081016:c4150743-4150447 [Pseudomonas sp. 2hn]
MEKRTPHCTLERIKALLAAERVRVTSTALRGARALGLDYPGMLEVISRLERADFYKSMTSYADHLVWQDVYRPLTAVGYV
YLKLTVVDDVLIVSFKEL

Download         Length: 297 bp

>T212591 NZ_CP107289:493300-493689 [Acinetobacter pittii]
TTGATAAAAGAATTAAATTTTGAGCTGAAATATAGCCGTGTCTCGGTAATATTTCAGCTTTTTGTTGGTTTGGGTTTAGC
AATCCTGCTTTATCAATTATTAACACCCATGTGGTGGCTATGCGCTGTCGTTCTTCTATTTATTGGTTTTATTTTCTTTT
TAAAGCAAGCACAAATATCTCAAATTGAATATTTAGATCAAAAATTATGGTCGGTTGCATATTTCTCGGAAAAAGAAATT
TACCGTGCAGAAATTACTAAAATAATTGATTATCAGTTGTTTGTAGTCCTTTATTTTGAAGGAGGACCTACGAAAATAGC
TATTGTTTGGTTCGATCAGCTTCCTATTCAGCAGTGGAAAAGGTTAAAAGTTTTAGAAAAGCTCTATTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14790.02 Da        Isoelectric Point: 5.6918

>AT212591 WP_050704793.1 NZ_CP081016:c4150444-4150043 [Pseudomonas sp. 2hn]
MRCPICGGAELAPDTQDMPYRYKGMSTLIPHVSGDYCPACGEAVLSHAEAMRVSDLMVEFDRKINAEAIDPAFIVAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTRPPVALIKLFKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT212591 NZ_CP107289:493036-493293 [Acinetobacter pittii]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCGTATGTAAAAAACTATTATTTAAAAGCTGATCCGGCAGAAAAAGCATTATTTGCAGAACTAGTTGATCAAGAAG
ATCCAGATTTATTAGATTGGTTCATGGAAGTTTCTGAGCCTCCACGTACTGAGTTACGTGAATTTATTTATAAACTAAAA
CAGTATGTACATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References