Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 335695..335890 Replicon chromosome
Accession NZ_CP080759
Organism Enterococcus faecalis strain M817

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag K2228_RS01740 Protein ID WP_015543884.1
Coordinates 335795..335890 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 335695..335760 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K2228_RS01725 331326..333068 + 1743 WP_250374026.1 PTS transporter subunit EIIC -
K2228_RS01730 333059..335092 + 2034 WP_002355275.1 BglG family transcription antiterminator -
K2228_RS01735 335103..335537 + 435 WP_002355276.1 PTS sugar transporter subunit IIA -
- 335695..335760 + 66 - - Antitoxin
K2228_RS01740 335795..335890 - 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
K2228_RS01745 336136..337908 + 1773 WP_002391520.1 PTS mannitol-specific transporter subunit IIBC -
K2228_RS01750 337923..338360 + 438 WP_002355279.1 PTS sugar transporter subunit IIA -
K2228_RS01755 338375..339529 + 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
K2228_RS01760 339598..340713 - 1116 WP_002377910.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T212325 WP_015543884.1 NZ_CP080759:c335890-335795 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T212325 NZ_CP107002:4032571-4032828 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 66 bp

>AT212325 NZ_CP080759:335695-335760 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References