Detailed information of TA system TA212308

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2032857..2033103
• Replicon: chromosome
• Accession: NZ_CP080629
• Organism: Bacillus subtilis strain YPS-32

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: K3G18_RS10105
• Protein ID: WP_109789044.1
• Coordinates: 2032857..2032949 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2032930..2033103 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K3G18_RS10090	2028016..2028351	+	336	WP_009967409.1	hypothetical protein	-
K3G18_RS10095	2028398..2032003	-	3606	WP_032721999.1	P-loop NTPase fold protein	-
K3G18_RS10100	2032236..2032568	-	333	WP_026009814.1	hypothetical protein	-
K3G18_RS10105	2032857..2032949	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2032930..2033103	-	174	-	-	Antitoxin
K3G18_RS10110	2033218..2034060	-	843	WP_003231327.1	hypothetical protein	-
K3G18_RS10115	2034260..2034718	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
K3G18_RS10120	2034728..2036530	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
K3G18_RS10125	2036632..2037189	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2008952..2041600	32648

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T212308 WP_109789044.1 NZ_CP080629:2032857-2032949 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T212308 NZ_CP107002:846265-846672 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Nucleotide

• Length: 174 bp

>AT212308 NZ_CP080629:c2033103-2032930 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin