Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 2804958..2806411 | Replicon | chromosome |
| Accession | NZ_CP080589 | ||
| Organism | Xanthomonas oryzae pv. oryzicola strain GX01 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A5C2EYQ5 |
| Locus tag | K2I41_RS12990 | Protein ID | WP_047339759.1 |
| Coordinates | 2804958..2805809 (-) | Length | 284 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A0C5V250 |
| Locus tag | K2I41_RS12995 | Protein ID | WP_024710981.1 |
| Coordinates | 2805806..2806411 (-) | Length | 202 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K2I41_RS12960 (K2I41_12895) | 2799998..2800960 | - | 963 | WP_044751530.1 | IS110 family transposase | - |
| K2I41_RS12965 (K2I41_12900) | 2801185..2801487 | - | 303 | WP_047339762.1 | hypothetical protein | - |
| K2I41_RS12970 (K2I41_12905) | 2802360..2802701 | - | 342 | WP_050585837.1 | ParB N-terminal domain-containing protein | - |
| K2I41_RS12975 (K2I41_12910) | 2802698..2803984 | - | 1287 | WP_228757531.1 | recombinase family protein | - |
| K2I41_RS12985 (K2I41_12915) | 2804401..2804871 | - | 471 | WP_149621647.1 | hypothetical protein | - |
| K2I41_RS12990 (K2I41_12920) | 2804958..2805809 | - | 852 | WP_047339759.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| K2I41_RS12995 (K2I41_12925) | 2805806..2806411 | - | 606 | WP_024710981.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| K2I41_RS13000 (K2I41_12930) | 2806655..2806999 | - | 345 | WP_150411545.1 | hypothetical protein | - |
| K2I41_RS13005 (K2I41_12935) | 2806953..2807465 | - | 513 | WP_161600049.1 | helix-turn-helix domain-containing protein | - |
| K2I41_RS13010 (K2I41_12940) | 2807766..2807942 | + | 177 | WP_014503024.1 | hypothetical protein | - |
| K2I41_RS13015 (K2I41_12945) | 2808253..2809338 | + | 1086 | WP_048485514.1 | sensor domain-containing diguanylate cyclase | - |
| K2I41_RS13020 (K2I41_12950) | 2809381..2809890 | - | 510 | WP_014503022.1 | chemotaxis protein CheW | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| flank | IS/Tn | - | - | 2799998..2800960 | 962 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 284 a.a. Molecular weight: 31056.91 Da Isoelectric Point: 7.0657
>T212217 WP_047339759.1 NZ_CP080589:c2805809-2804958 [Xanthomonas oryzae pv. oryzicola]
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR
Download Length: 852 bp
>T212217 NZ_CP106998:1800483-1800737 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Antitoxin
Download Length: 202 a.a. Molecular weight: 22257.92 Da Isoelectric Point: 9.9253
>AT212217 WP_024710981.1 NZ_CP080589:c2806411-2805806 [Xanthomonas oryzae pv. oryzicola]
MLSDTHTQRVLDLASQKGLLRASDLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVRLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE
MLSDTHTQRVLDLASQKGLLRASDLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVRLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE
Download Length: 606 bp
>AT212217 NZ_CP106998:1800235-1800486 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A5C2EYQ5 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5V250 |