Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2159963..2160179 Replicon chromosome
Accession NZ_CP080564
Organism Staphylococcus aureus strain HL16278

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag JMO07_RS10600 Protein ID WP_001802298.1
Coordinates 2160075..2160179 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2159963..2160018 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMO07_RS10580 2156166..2156831 - 666 WP_001024095.1 SDR family oxidoreductase -
JMO07_RS10585 2156983..2157303 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
JMO07_RS10590 2157305..2158285 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
JMO07_RS10595 2158551..2159642 + 1092 WP_000495681.1 hypothetical protein -
- 2159963..2160018 + 56 - - Antitoxin
JMO07_RS10600 2160075..2160179 - 105 WP_001802298.1 hypothetical protein Toxin
JMO07_RS10605 2160859..2161017 + 159 WP_001792784.1 hypothetical protein -
JMO07_RS10610 2161675..2162532 - 858 WP_000370928.1 HAD family hydrolase -
JMO07_RS10615 2162600..2163382 - 783 WP_000908189.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T212163 WP_001802298.1 NZ_CP080564:c2160179-2160075 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T212163 NZ_CP106996:714669-714965 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 56 bp

>AT212163 NZ_CP080564:2159963-2160018 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References