Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 2614148..2614296 Replicon chromosome
Accession NC_007168
Organism Staphylococcus haemolyticus JCSC1435

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag SH_RS13630 Protein ID WP_011276848.1
Coordinates 2614148..2614243 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2614261..2614296 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SH_RS12585 2609875..2610108 + 234 WP_016931184.1 hypothetical protein -
SH_RS12590 2610216..2610533 - 318 Protein_2472 IS200/IS605-like element ISSep3 family transposase -
SH_RS13835 2611226..2611483 + 258 Protein_2473 replication initiation protein -
SH_RS12605 2612087..2612617 + 531 WP_011276845.1 N-acetyltransferase -
SH_RS12610 2612857..2613240 + 384 WP_011276846.1 effector binding domain-containing protein -
SH_RS12615 2613379..2613683 + 305 Protein_2476 hypothetical protein -
SH_RS13840 2613807..2613953 + 147 WP_000668388.1 hypothetical protein -
SH_RS13630 2614148..2614243 + 96 WP_011276848.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2614261..2614296 + 36 - - Antitoxin
SH_RS12620 2614437..2615096 + 660 WP_011276849.1 nucleotidyltransferase -
SH_RS12625 2615342..2615944 + 603 WP_011276850.1 hypothetical protein -
SH_RS12630 2616089..2616904 - 816 WP_000160701.1 AAA family ATPase -
SH_RS12635 2616897..2618339 - 1443 WP_000790709.1 DDE-type integrase/transposase/recombinase -
SH_RS12640 2618311..2618904 - 594 WP_000690636.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2610213..2610533 320


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3623.38 Da        Isoelectric Point: 9.5124

>T21208 WP_011276848.1 NC_007168:2614148-2614243 [Staphylococcus haemolyticus JCSC1435]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Download         Length: 96 bp

>T21208 NC_007168:2614148-2614243 [Staphylococcus haemolyticus JCSC1435]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin


Download         Length: 36 bp

>AT21208 NC_007168:2614261-2614296 [Staphylococcus haemolyticus JCSC1435]
TACAACAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References