Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 2331511..2331659 Replicon chromosome
Accession NC_007168
Organism Staphylococcus haemolyticus JCSC1435

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag SH_RS13605 Protein ID WP_011276560.1
Coordinates 2331511..2331606 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2331624..2331659 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SH_RS11110 2327355..2327771 - 417 WP_011276552.1 DUF1934 family protein -
SH_RS13595 2328060..2328155 + 96 WP_011276553.1 type I toxin-antitoxin system Fst family toxin -
SH_RS13370 2328669..2329175 + 507 Protein_2189 protein rep -
SH_RS11120 2330028..2330246 + 219 WP_011276556.1 hypothetical protein -
SH_RS13710 2330914..2331162 + 249 WP_033080158.1 hypothetical protein -
SH_RS13605 2331511..2331606 + 96 WP_011276560.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2331624..2331659 + 36 - - Antitoxin
SH_RS11130 2331749..2332519 - 771 WP_011276561.1 ABC transporter permease -
SH_RS11135 2332521..2333216 - 696 WP_011276562.1 ATP-binding cassette domain-containing protein -
SH_RS11140 2333752..2335218 + 1467 WP_000438873.1 ABC-F type ribosomal protection protein Msr(A) -
SH_RS11145 2335317..2336216 + 900 WP_000196697.1 Mph(C) family macrolide 2'-phosphotransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3670.48 Da        Isoelectric Point: 11.0582

>T21205 WP_011276560.1 NC_007168:2331511-2331606 [Staphylococcus haemolyticus JCSC1435]
MLEIFVHITTTVISGCIIALFTHWLRNRKKK

Download         Length: 96 bp

>T21205 NC_007168:2331511-2331606 [Staphylococcus haemolyticus JCSC1435]
ATGTTGGAAATCTTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAGAAAAAATAG

Antitoxin


Download         Length: 36 bp

>AT21205 NC_007168:2331624-2331659 [Staphylococcus haemolyticus JCSC1435]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References