Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4495910..4496564 Replicon chromosome
Accession NZ_CP080512
Organism Pseudomonas protegens strain CM-YJ10_15-44

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag K1T36_RS20275 Protein ID WP_220222941.1
Coordinates 4495910..4496260 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag K1T36_RS20280 Protein ID WP_053152691.1
Coordinates 4496247..4496564 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K1T36_RS31980 4492009..4492629 + 621 WP_258571599.1 hypothetical protein -
K1T36_RS20265 (K1T36_20265) 4492669..4494201 + 1533 WP_152686307.1 NADH-quinone oxidoreductase subunit M -
K1T36_RS20270 (K1T36_20270) 4494209..4495672 + 1464 WP_011062196.1 NADH-quinone oxidoreductase subunit NuoN -
K1T36_RS20275 (K1T36_20275) 4495910..4496260 + 351 WP_220222941.1 toxin Toxin
K1T36_RS20280 (K1T36_20280) 4496247..4496564 + 318 WP_053152691.1 transcriptional regulator Antitoxin
K1T36_RS20285 (K1T36_20285) 4496633..4498015 - 1383 WP_015636301.1 cysteine--tRNA ligase -
K1T36_RS20290 (K1T36_20290) 4498034..4499734 - 1701 WP_220222942.1 glutamine--tRNA ligase/YqeY domain fusion protein -
K1T36_RS20295 (K1T36_20295) 4500005..4500508 + 504 WP_011062201.1 peptidylprolyl isomerase -
K1T36_RS20300 (K1T36_20300) 4500505..4501257 + 753 WP_015636303.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13980.13 Da        Isoelectric Point: 9.5952

>T211976 WP_220222941.1 NZ_CP080512:4495910-4496260 [Pseudomonas protegens]
MNALFIELPAFARYRKDFLDDELFCELQIELLRHPHAGVLIKGTGGLRKMRFVDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T211976 NZ_CP106890:907687-908097 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12050.92 Da        Isoelectric Point: 10.4439

>AT211976 WP_053152691.1 NZ_CP080512:4496247-4496564 [Pseudomonas protegens]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITAAEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRAIP
NAQATTLIRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT211976 NZ_CP106890:907440-907706 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References