Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2074213..2074800 Replicon chromosome
Accession NZ_CP080387
Organism Agrobacterium cucumeris strain O132

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KZ699_RS10110 Protein ID WP_210347428.1
Coordinates 2074213..2074497 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KZ699_RS10115 Protein ID WP_174030079.1
Coordinates 2074549..2074800 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZ699_RS10085 (KZ699_10035) 2069661..2070323 + 663 WP_269702245.1 sulfite exporter TauE/SafE family protein -
KZ699_RS10090 (KZ699_10040) 2070461..2071594 + 1134 WP_269701964.1 alpha-hydroxy acid oxidase -
KZ699_RS10095 (KZ699_10045) 2071809..2072153 - 345 WP_110756171.1 multidrug efflux SMR transporter -
KZ699_RS10100 (KZ699_10050) 2072150..2072722 - 573 WP_269701960.1 TetR/AcrR family transcriptional regulator -
KZ699_RS10105 (KZ699_10055) 2072926..2074209 + 1284 WP_269702243.1 D-alanyl-D-alanine carboxypeptidase -
KZ699_RS10110 (KZ699_10060) 2074213..2074497 - 285 WP_210347428.1 Txe/YoeB family addiction module toxin Toxin
KZ699_RS10115 (KZ699_10065) 2074549..2074800 - 252 WP_174030079.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KZ699_RS10120 (KZ699_10070) 2074853..2075602 - 750 WP_269701956.1 metallophosphoesterase family protein -
KZ699_RS10125 (KZ699_10075) 2075608..2075964 - 357 WP_269701954.1 hydroxyisourate hydrolase -
KZ699_RS10130 (KZ699_10080) 2075961..2076461 - 501 WP_269701952.1 ureidoglycolate lyase -
KZ699_RS10135 (KZ699_10085) 2076465..2076827 - 363 WP_065113955.1 DUF86 domain-containing protein -
KZ699_RS10140 (KZ699_10090) 2076824..2077114 - 291 WP_269701948.1 nucleotidyltransferase family protein -
KZ699_RS10145 (KZ699_10095) 2077168..2077665 - 498 WP_269701946.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
KZ699_RS10150 (KZ699_10100) 2077665..2078588 - 924 WP_269701944.1 allantoinase PuuE -
KZ699_RS10155 (KZ699_10105) 2078794..2079501 - 708 WP_142840454.1 DUF1045 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(11-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11487.22 Da        Isoelectric Point: 9.5189

>T211839 WP_210347428.1 NZ_CP080387:c2074497-2074213 [Agrobacterium cucumeris]
MQQKGSIALGWSHEGWEDYLHWQKYDRKMLERINELIKDCRRHPFEGIGKPEPLRFQLKGLWSRRISQEHRLVYELRGEG
EKAVLIIHQCRFHY

Download         Length: 285 bp

>T211839 NZ_CP106786:c2817570-2816248 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCTGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9416.65 Da        Isoelectric Point: 4.5242

>AT211839 WP_174030079.1 NZ_CP080387:c2074800-2074549 [Agrobacterium cucumeris]
MRTVMFSKARESLASLLDEVSQDRVTVEIVRRDKPSAVLIDKDEYEGLMETLHLCSSPENFARLRKSMSDVDGGVFESHD
LID

Download         Length: 252 bp

>AT211839 NZ_CP106786:c2817836-2817570 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References