211709

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4294198..4294852 Replicon chromosome
Accession NZ_CP080330
Organism Pseudomonas sp. ArH3a

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag K0P33_RS19535 Protein ID WP_094950600.1
Coordinates 4294198..4294548 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag K0P33_RS19540 Protein ID WP_094950599.1
Coordinates 4294538..4294852 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K0P33_RS19525 (K0P33_19455) 4290955..4292487 + 1533 WP_064452906.1 NADH-quinone oxidoreductase subunit M -
K0P33_RS19530 (K0P33_19460) 4292495..4293958 + 1464 WP_094950601.1 NADH-quinone oxidoreductase subunit NuoN -
K0P33_RS19535 (K0P33_19465) 4294198..4294548 + 351 WP_094950600.1 toxin Toxin
K0P33_RS19540 (K0P33_19470) 4294538..4294852 + 315 WP_094950599.1 transcriptional regulator Antitoxin
K0P33_RS19545 (K0P33_19475) 4295076..4295828 - 753 WP_094950598.1 outer membrane beta-barrel protein -
K0P33_RS19550 (K0P33_19480) 4295953..4296786 - 834 WP_242150630.1 arylamine N-acetyltransferase -
K0P33_RS19555 (K0P33_19485) 4296907..4297143 + 237 WP_094950596.1 hypothetical protein -
K0P33_RS19560 (K0P33_19490) 4297208..4297405 - 198 WP_242150633.1 DUF6021 family protein -
K0P33_RS19565 (K0P33_19495) 4297421..4297597 - 177 WP_176462926.1 hypothetical protein -
K0P33_RS19570 (K0P33_19500) 4297716..4298237 + 522 WP_094950594.1 DUF3087 domain-containing protein -
K0P33_RS19575 (K0P33_19505) 4298243..4299370 - 1128 WP_242150636.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13769.66 Da        Isoelectric Point: 9.3839

>T211709 WP_094950600.1 NZ_CP080330:4294198-4294548 [Pseudomonas sp. ArH3a]
MDALFIELPAFERHRKDYLSDELFQGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLAPHHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

>T211709 NZ_CP106744:c5587347-5587048 [Pseudomonas aeruginosa]
ATGGTCGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11731.55 Da        Isoelectric Point: 10.7844

>AT211709 WP_094950599.1 NZ_CP080330:4294538-4294852 [Pseudomonas sp. ArH3a]
MKREIFSELVEGFDALAEERQGKVTLRTHKVRLNNLAPLTAEEVVAVRQQLNLSRSVFAMYLRTNVRTLENWEQGRAKPN
AQAATLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT211709 NZ_CP106744:c5587051-5586761 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References