Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2322311..2322527 Replicon chromosome
Accession NZ_CP080249
Organism Staphylococcus aureus strain NV_1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag KZW86_RS11775 Protein ID WP_001802298.1
Coordinates 2322423..2322527 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2322311..2322366 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZW86_RS11750 2318517..2319182 - 666 WP_001024092.1 SDR family oxidoreductase -
KZW86_RS11755 2319334..2319654 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
KZW86_RS11760 2319656..2320633 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
KZW86_RS11765 2320899..2321990 + 1092 WP_000495669.1 hypothetical protein -
KZW86_RS11770 2322310..2322384 + 75 Protein_2280 hypothetical protein -
KZW86_RS11775 2322423..2322527 - 105 WP_001802298.1 hypothetical protein Toxin
KZW86_RS11780 2323207..2323365 + 159 WP_001792784.1 hypothetical protein -
KZW86_RS11785 2324023..2324880 - 858 WP_234769199.1 HAD family hydrolase -
KZW86_RS11790 2324948..2325730 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T211426 WP_001802298.1 NZ_CP080249:c2322527-2322423 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T211426 NZ_CP104858:2441424-2441711 [Salmonella sp. 3C]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 56 bp

>AT211426 NZ_CP080249:2322311-2322366 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References