Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4165517..4165763 Replicon chromosome
Accession NZ_CP079891
Organism Escherichia fergusonii strain 5zf15-2-1

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag KYD87_RS20545 Protein ID WP_000956458.1
Coordinates 4165611..4165763 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 4165517..4165569 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KYD87_RS20530 4161027..4162826 + 1800 WP_182210801.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
KYD87_RS20535 4162826..4164538 + 1713 WP_046081202.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
KYD87_RS20540 4164612..4165346 + 735 WP_182210804.1 phosphoadenosine phosphosulfate reductase -
- 4165517..4165569 - 53 - - Antitoxin
KYD87_RS20545 4165611..4165763 + 153 WP_000956458.1 Hok/Gef family protein Toxin
KYD87_RS20550 4165956..4168656 + 2701 Protein_4008 CRISPR-associated helicase Cas3' -
KYD87_RS20555 4168754..4170316 + 1563 WP_182210808.1 type I-E CRISPR-associated protein Cse1/CasA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T210349 WP_000956458.1 NZ_CP079891:4165611-4165763 [Escherichia fergusonii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

>T210349 NZ_CP104503:c1176532-1176278 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 53 bp

>AT210349 NZ_CP079891:c4165569-4165517 [Escherichia fergusonii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References