Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 976704..976950 Replicon chromosome
Accession NZ_CP079884
Organism Escherichia fergusonii strain 6S41-1

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag KYC43_RS04690 Protein ID WP_000956458.1
Coordinates 976798..976950 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 976704..976756 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KYC43_RS04675 972214..974013 + 1800 WP_182210801.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
KYC43_RS04680 974013..975725 + 1713 WP_046081202.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
KYC43_RS04685 975799..976533 + 735 WP_182210804.1 phosphoadenosine phosphosulfate reductase -
- 976704..976756 - 53 - - Antitoxin
KYC43_RS04690 976798..976950 + 153 WP_000956458.1 Hok/Gef family protein Toxin
KYC43_RS04695 977143..978255 - 1113 WP_001300563.1 IS4-like element IS421 family transposase -
KYC43_RS04700 978492..981192 + 2701 Protein_907 CRISPR-associated helicase Cas3' -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T210280 WP_000956458.1 NZ_CP079884:976798-976950 [Escherichia fergusonii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

>T210280 NZ_CP079884:976798-976950 [Escherichia fergusonii]
ATGCTGACAAAATATGCCCTTGTGGCAATCATCGTACTGTGTTGTACAGTACTGGGATTCACGCTGATGGTAGGCGACTC
GTTGTGTGAGTTGAGTATCAGAGAACGTGGTATGGAGTTTAAGGCAGTTCTCGCTTACGAATCGAAGAAGTAG

Antitoxin


Download         Length: 53 bp

>AT210280 NZ_CP079884:c976756-976704 [Escherichia fergusonii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References