Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3561227..3562042 Replicon chromosome
Accession NZ_CP079882
Organism Proteus terrae strain 20Q172tw

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag KZA80_RS16745 Protein ID WP_075673429.1
Coordinates 3561569..3562042 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag KZA80_RS16740 Protein ID WP_075673430.1
Coordinates 3561227..3561562 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZA80_RS16720 (KZA80_16690) 3556916..3558340 + 1425 WP_072069056.1 aspartate ammonia-lyase -
KZA80_RS16725 (KZA80_16695) 3558499..3559824 + 1326 WP_036934359.1 anaerobic C4-dicarboxylate transporter -
KZA80_RS16730 (KZA80_16700) 3560008..3560580 + 573 WP_260797485.1 transcriptional regulator -
KZA80_RS16740 (KZA80_16710) 3561227..3561562 + 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
KZA80_RS16745 (KZA80_16715) 3561569..3562042 + 474 WP_075673429.1 type II toxin-antitoxin system YhaV family toxin Toxin
KZA80_RS16750 (KZA80_16720) 3562353..3563000 + 648 WP_164530724.1 type II CAAX endopeptidase family protein -
KZA80_RS16755 (KZA80_16725) 3563303..3563938 + 636 WP_156734149.1 DUF1449 family protein -
KZA80_RS16760 (KZA80_16730) 3564025..3566220 + 2196 WP_099659727.1 flotillin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18639.26 Da        Isoelectric Point: 9.2715

>T210271 WP_075673429.1 NZ_CP079882:3561569-3562042 [Proteus terrae]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

>T210271 NZ_CP104484:365061-365336 [Salmonella enterica]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGAGCCTGACTGGATTCTTATTTATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT210271 WP_075673430.1 NZ_CP079882:3561227-3561562 [Proteus terrae]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp

>AT210271 NZ_CP104484:364798-365058 [Salmonella enterica]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGGACCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGCATAC
CCAATGAGTTAACGTCCCGAACGATAGAAAATAGCGAAGCTGGCGTTGATATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References