Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 134100..134593 Replicon chromosome
Accession NZ_CP079862
Organism Frankia sp. ArI3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KZA76_RS00480 Protein ID WP_044886637.1
Coordinates 134339..134593 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KZA76_RS00475 Protein ID WP_255354322.1
Coordinates 134100..134342 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZA76_RS00465 130729..131607 - 879 WP_044886640.1 formate dehydrogenase accessory sulfurtransferase FdhD -
KZA76_RS00470 131607..133952 - 2346 WP_255649466.1 FdhF/YdeP family oxidoreductase -
KZA76_RS00475 134100..134342 + 243 WP_255354322.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KZA76_RS00480 134339..134593 + 255 WP_044886637.1 Txe/YoeB family addiction module toxin Toxin
KZA76_RS00485 134638..135408 - 771 WP_044886663.1 enoyl-CoA hydratase-related protein -
KZA76_RS00490 135632..136084 + 453 WP_044886636.1 pyridoxamine 5'-phosphate oxidase family protein -
KZA76_RS00495 136111..136593 - 483 WP_220386521.1 endo alpha-1,4 polygalactosaminidase -
KZA76_RS00500 136590..136952 - 363 WP_220386522.1 endo alpha-1,4 polygalactosaminidase -
KZA76_RS00505 136989..137669 - 681 WP_044886634.1 NAD(P)H-dependent oxidoreductase -
KZA76_RS00510 137741..139009 - 1269 WP_044886662.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10324.73 Da        Isoelectric Point: 9.7526

>T210253 WP_044886637.1 NZ_CP079862:134339-134593 [Frankia sp. ArI3]
VKLVWDENAWQDYLWWRTENRKILKRINVLIQDIARNGNDGIGKPEPLKHGFQGYWSRRINDEHRLIYKISDDQIRIAQC
RYHY

Download         Length: 255 bp

>T210253 NZ_CP104479:c4272433-4272149 [Salmonella enterica]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTCGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8907.97 Da        Isoelectric Point: 4.4805

>AT210253 WP_255354322.1 NZ_CP079862:134100-134342 [Frankia sp. ArI3]
MSYSESRARYAEVLTAVADDREEVVITRAGHEPVVIVSLDDYQSLKETAYLLRSPENARRLLAAIDRLESGAGTVRDLVE

Download         Length: 243 bp

>AT210253 NZ_CP104479:c4272665-4272423 [Salmonella enterica]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCACTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References