Detailed information of TA system TA210188

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 153069..153327
• Replicon: chromosome
• Accession: NZ_CP079837
• Organism: Salmonella enterica subsp. salamae strain LHICA_SA2

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: -
• Locus tag: JMJ84_RS00715
• Protein ID: WP_219141511.1
• Coordinates: 153175..153327 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	153069..153124 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JMJ84_RS00695	148254..149188	-	935	Protein_139	acyltransferase	-
JMJ84_RS00700	149414..149716	+	303	WP_079789791.1	YsaB family lipoprotein	-
JMJ84_RS00705	149855..150766	+	912	WP_001168556.1	glycine--tRNA ligase subunit alpha	-
JMJ84_RS00710	150776..152845	+	2070	WP_001291746.1	glycine--tRNA ligase subunit beta	-
-	153069..153124	-	56	-	-	Antitoxin
JMJ84_RS00715	153175..153327	+	153	WP_219141511.1	type I toxin-antitoxin system toxin HokA	Toxin
JMJ84_RS00720	153453..153992	-	540	WP_111770182.1	copper-binding periplasmic metallochaperone CueP	-
JMJ84_RS00725	154167..154379	-	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
JMJ84_RS00730	154667..154957	-	291	WP_000455790.1	HTH-type transcriptional regulator	-
JMJ84_RS00735	155395..156105	+	711	WP_000190524.1	DUF3053 domain-containing protein	-
JMJ84_RS00740	156155..157129	-	975	WP_219141512.1	glyoxylate/hydroxypyruvate reductase GhrB	-
JMJ84_RS00745	157348..158010	-	663	WP_000747548.1	OmpA family lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5682.79 Da
• Isoelectric Point: 6.9149

>T210188 WP_219141511.1 NZ_CP079837:153175-153327 [Salmonella enterica subsp. salamae]
MPQKGMLYSLIVICLTILLFTWMVRDSLCELHIRQGNNELAATLACDSKQ

Nucleotide

• Length: 153 bp

>T210188 NZ_CP104467:c6598435-6598085 [Paenibacillus sp. SS4]
GTGATTGTGAAACGTGGTGATGTATTTTTCGCAGATCTTTCGCCGGTAGTAGGGTCAGAGCAGGGAGGGGTTCGTCCTGT
TCTAGTGATCCAAAATGATATCGGCAACCGCTTTAGCCCAACCGTGATTGTTGCAGCGATTACAGCTCAAATCCAGAAGG
CGAAGCTTCCCACGCATGTAGAGATCGATGCGGAAACGCATGGTTTCGATCGAGATTCGGTGATTCTGCTTGAACAAATC
AGAACGATCGATAAGCAACGGCTGACGGACAAAATTACGCATTTGGACGAAGAAACGATGCGCAAGGTGGACGACGCTTT
GCAGATTAGTGTGGGACTGATAGAGTTTTGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT210188 NZ_CP079837:c153124-153069 [Salmonella enterica subsp. salamae]
GTTCAAGCATAGAGGTGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin