Detailed information of TA system TA210170

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 190420..190678
• Replicon: chromosome
• Accession: NZ_CP079836
• Organism: Salmonella enterica subsp. salamae strain LHICA_SA1

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: -
• Locus tag: JMJ86_RS00895
• Protein ID: WP_001135702.1
• Coordinates: 190526..190678 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	190420..190475 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JMJ86_RS00875	185604..186599	-	996	WP_079815085.1	acyltransferase	-
JMJ86_RS00880	186765..187067	+	303	WP_000178127.1	YsaB family lipoprotein	-
JMJ86_RS00885	187206..188117	+	912	WP_001168556.1	glycine--tRNA ligase subunit alpha	-
JMJ86_RS00890	188127..190196	+	2070	WP_079974321.1	glycine--tRNA ligase subunit beta	-
-	190420..190475	-	56	-	-	Antitoxin
JMJ86_RS00895	190526..190678	+	153	WP_001135702.1	type I toxin-antitoxin system toxin HokA	Toxin
JMJ86_RS00900	190804..191343	-	540	WP_046093855.1	copper-binding periplasmic metallochaperone CueP	-
JMJ86_RS00905	191516..191728	-	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
JMJ86_RS00910	192016..192306	-	291	WP_000455790.1	HTH-type transcriptional regulator	-
JMJ86_RS00915	192744..193454	+	711	WP_000190525.1	DUF3053 domain-containing protein	-
JMJ86_RS00920	193504..194478	-	975	WP_219175825.1	glyoxylate/hydroxypyruvate reductase GhrB	-
JMJ86_RS00925	194696..195358	-	663	WP_000747548.1	OmpA family lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5650.73 Da
• Isoelectric Point: 6.9149

>T210170 WP_001135702.1 NZ_CP079836:190526-190678 [Salmonella enterica subsp. salamae]
MPQKGMLYSLIVICLTILLFTWIVRDSLCELHIRQGNNELAASLACDSKQ

Nucleotide

• Length: 153 bp

>T210170 NZ_CP104447:275134-275415 [Acinetobacter baumannii]
ATGGCTATTAAACTTCGCAAATGGGACAGTGCTGAGCATCTTAAAACAGAGGATGATATGCAGGCTTACTTACAAGCATG
TATTGAAGAATCTAATGGCGATGCCGCATTCATTGCAAAGGCTTTAGGTAACATTGCAAAAGCTAAAGGAATGGCTCAAT
TATCACGAGATACAGGCTTAGGCCGAGAAAGTCTTTATAAAGCACTTTCTGGTGATGTTAACCCTAGTTTTGATACTGTG
ATTAAAGTTGTAAAAGCACTGAATTTACGCTTAGCAATTTAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT210170 NZ_CP079836:c190475-190420 [Salmonella enterica subsp. salamae]
GTTCAAGCATAGAGGTGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin