Detailed information of TA system TA209774

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2762036..2762253
• Replicon: chromosome
• Accession: NZ_CP079715
• Organism: Staphylococcus aureus strain V8

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: KX797_RS13970
• Protein ID: WP_001802298.1
• Coordinates: 2762149..2762253 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2762036..2762091 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KX797_RS13950	2758173..2758838	-	666	WP_001024094.1	SDR family oxidoreductase	-
KX797_RS13955	2758990..2759310	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
KX797_RS13960	2759312..2760292	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
KX797_RS13965	2760558..2761649	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2762036..2762091	+	56	-	-	Antitoxin
KX797_RS13970	2762149..2762253	-	105	WP_001802298.1	hypothetical protein	Toxin
KX797_RS13975	2762414..2762897	-	484	Protein_2722	recombinase family protein	-
KX797_RS13980	2762940..2764076	-	1137	WP_000115564.1	SAP domain-containing protein	-
KX797_RS13985	2764365..2764457	+	93	WP_001790138.1	hypothetical protein	-
KX797_RS14390	2764746..2764930	+	185	Protein_2725	exotoxin	-
KX797_RS13990	2765162..2766019	-	858	WP_000370924.1	HAD family hydrolase	-
KX797_RS13995	2766087..2766869	-	783	WP_000908177.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T209774 WP_001802298.1 NZ_CP079715:c2762253-2762149 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T209774 NZ_CP104307:c422070-421828 [Flavobacterium sp. TR2]
ATGAGTAAGATTGATAAACTTATTGAAAAGTTAAAATCAAAGCCTAAGGATTTTTCTTGGGATGAAATGGTGAAAGTTTT
AAAATATTTTGGATACGAGCAGATTTCACAAGGAAAAACAGGTGGTTCAAGAAGAAAATTTGTAAATGAAAATAAACAGA
TTATAAGTTTGCATGAACCGCATCCGCAGAAGGTTTTGAAAAGCTATCAGCTTGATATTATTATTGAACATTTGGAATTG
TAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT209774 NZ_CP079715:2762036-2762091 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin