209763

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1409916..1410330 Replicon chromosome
Accession NZ_CP079715
Organism Staphylococcus aureus strain V8

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KX797_RS07105 Protein ID WP_031929211.1
Coordinates 1409916..1410167 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KX797_RS07110 Protein ID WP_000028424.1
Coordinates 1410157..1410330 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KX797_RS07050 (1405618) 1405618..1406388 + 771 WP_000190224.1 conserved phage C-terminal domain-containing protein -
KX797_RS07055 (1406398) 1406398..1407177 + 780 WP_000803065.1 ATP-binding protein -
KX797_RS07060 (1407171) 1407171..1407332 + 162 WP_000237153.1 hypothetical protein -
KX797_RS07065 (1407345) 1407345..1407566 + 222 WP_001123673.1 DUF3269 family protein -
KX797_RS07070 (1407577) 1407577..1407981 + 405 WP_000049804.1 DUF1064 domain-containing protein -
KX797_RS07075 (1407986) 1407986..1408171 + 186 WP_001187234.1 DUF3113 family protein -
KX797_RS07080 (1408172) 1408172..1408531 + 360 WP_000029370.1 SA1788 family PVL leukocidin-associated protein -
KX797_RS07085 (1408532) 1408532..1408780 + 249 WP_001126828.1 SAV1978 family virulence-associated passenger protein -
KX797_RS07090 (1408795) 1408795..1409196 + 402 WP_000695748.1 hypothetical protein -
KX797_RS07095 (1409193) 1409193..1409642 + 450 WP_000982708.1 YopX family protein -
KX797_RS07100 (1409639) 1409639..1409923 + 285 WP_001105620.1 hypothetical protein -
KX797_RS07105 (1409916) 1409916..1410167 + 252 WP_031929211.1 DUF1024 family protein Toxin
KX797_RS07110 (1410157) 1410157..1410330 + 174 WP_000028424.1 hypothetical protein Antitoxin
KX797_RS07115 (1410331) 1410331..1410492 + 162 WP_000889682.1 hypothetical protein -
KX797_RS07120 (1410507) 1410507..1411040 + 534 WP_031807824.1 dUTPase -
KX797_RS07125 (1411077) 1411077..1411283 + 207 WP_000195820.1 DUF1381 domain-containing protein -
KX797_RS07130 (1411280) 1411280..1411453 + 174 WP_096659372.1 transcriptional activator RinB -
KX797_RS07135 (1411454) 1411454..1411855 + 402 WP_000286968.1 hypothetical protein -
KX797_RS07140 (1412208) 1412208..1412702 + 495 WP_000594079.1 terminase small subunit -
KX797_RS07145 (1412695) 1412695..1413918 + 1224 WP_001037586.1 PBSX family phage terminase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk / selq 1356260..1438862 82602


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF1024

(1-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9420.29 Da        Isoelectric Point: 3.8146

>T209763 WP_031929211.1 NZ_CP079715:1409916-1410167 [Staphylococcus aureus]
MDNREQIEQSVISASAYNGNDTEGLIKEIEDVYKKAQAFDEILEGMTNAIQHSVKEGIELDEAVGIMTGQVVYKYEEEQE
NEY

Download         Length: 252 bp

>T209763 NZ_CP104302:1304115-1304477 [Mycolicibacterium brumae]
ATGATTTTGGTCGACACCTCGGTGTGGATCGATCACCTACACGCCCCTGACGCGCGGCTATCGGCACGGCTGGAAGCCGA
CGATGTGGGTTGCCATCAGTTGGTGATCGAGGAACTGGCGCTCGGGTCGATCGCGAATCGGGCGGAGGTGCTGGCATTGC
TGGCGAACCTGACCCGCTTCCCGGAGGTTGGCCACCGCGAGATCCTTCACATCACCGATCGGCGAAGATTGTGGGGGCGA
GGCCTTAGCGCCGTGGATGTTCACTTGATGGCCGCGGTCGCATTGGTTGCCGGCGCCAAGTTGTGGACACGAGACAAGCG
ACTTGGACGGGTTGCGGCGGAGTGCGGCGTGACCTTGTTCTGA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6468.29 Da        Isoelectric Point: 4.2484

>AT209763 WP_000028424.1 NZ_CP079715:1410157-1410330 [Staphylococcus aureus]
MSISVGDKVYNHETNESLEIVQLVGDIRDTHYKLSDDSVISIIDFITKPIYLIKGDE

Download         Length: 174 bp

>AT209763 NZ_CP104302:1303921-1304118 [Mycolicibacterium brumae]
ATGCGGACGACGGTCACTATCGACGATGAATTGCTGGAGCGCGCCGCGGAACTGACCGGAGTGCGTGAGAACGTCGCGCT
GCTCAAACGTGGGCTGCAGACGTTGATCCGGGTGGAGAGCGCTCGGCGCCTGGCGGCGCTGGGTGGATCCGACCCGGACG
CCGCGTCGGCGCCGCGGCGGCGTGGCGAGCCGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References