Detailed information of TA system TA209470

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 1287549..1288063
• Replicon: chromosome
• Accession: NZ_CP079235
• Organism: Bifidobacterium pseudocatenulatum strain YIT11952

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: KYE73_RS05440
• Protein ID: WP_055054685.1
• Coordinates: 1287549..1287803 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: KYE73_RS05445
• Protein ID: WP_195552582.1
• Coordinates: 1287803..1288063 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KYE73_RS05425 (KYE73_05410)	1283822..1286026	+	2205	WP_226848673.1	type IA DNA topoisomerase	-
KYE73_RS05430 (KYE73_05415)	1286212..1286385	+	174	WP_226645622.1	hypothetical protein	-
KYE73_RS05435 (KYE73_05420)	1286452..1287348	+	897	WP_226645619.1	Fic family protein	-
KYE73_RS05440 (KYE73_05425)	1287549..1287803	-	255	WP_055054685.1	Txe/YoeB family addiction module toxin	Toxin
KYE73_RS05445 (KYE73_05430)	1287803..1288063	-	261	WP_195552582.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
KYE73_RS05450 (KYE73_05435)	1288785..1289102	-	318	WP_065438751.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (3-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (4-75)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10013.51 Da
• Isoelectric Point: 7.9920

>T209470 WP_055054685.1 NZ_CP079235:c1287803-1287549 [Bifidobacterium pseudocatenulatum]
IMLRWTDDAWNDYLYWQVQDKKTLKRVNALIRDAMRSPFAGLGKPEPLKWELQGAWSRRIDSANRLVYMIEDGDLCILSV
RDHY

Nucleotide

• Length: 255 bp

>T209470 NZ_CP104114:c647426-647085 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTATCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCTA
CCGGCACGGCGGTAGATGTCAAAGTGATGAAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGAAGAGAGCGAG
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAAGCAGGTGCGGGAATTTATTGGGGTGATTGC
GGGTAAACAGAAAGTCGCCTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9828.12 Da
• Isoelectric Point: 5.0462

>AT209470 WP_195552582.1 NZ_CP079235:c1288063-1287803 [Bifidobacterium pseudocatenulatum]
MVTAVAYTNFRKDLKSYLRRVNDDADMLLITNKDPRDNVVVMSADDYDSLMETLRVYQNPGLFDKVRRGMAQVRSGSTDL
HDLVGE

Nucleotide

• Length: 261 bp

>AT209470 NZ_CP104114:647421-647497 [Escherichia coli]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT