Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2877871..2878380 Replicon chromosome
Accession NZ_CP079195
Organism Polaribacter sp. NJDZ03

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KV700_RS12255 Protein ID WP_218598048.1
Coordinates 2878120..2878380 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KV700_RS12250 Protein ID WP_218598047.1
Coordinates 2877871..2878119 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KV700_RS12230 2872961..2873626 - 666 WP_166383545.1 LysE family transporter -
KV700_RS12235 2874087..2875133 - 1047 WP_218598045.1 ferredoxin--NADP reductase -
KV700_RS12240 2875148..2876137 - 990 WP_166383541.1 aspartate-semialdehyde dehydrogenase -
KV700_RS12245 2876794..2877825 + 1032 WP_218598046.1 rhodanese-related sulfurtransferase -
KV700_RS12250 2877871..2878119 + 249 WP_218598047.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KV700_RS12255 2878120..2878380 + 261 WP_218598048.1 Txe/YoeB family addiction module toxin Toxin
KV700_RS12260 2878449..2879696 + 1248 WP_218598049.1 peptidase U32 family protein -
KV700_RS12265 2879696..2879926 + 231 WP_166383533.1 ferredoxin -
KV700_RS12270 2880301..2881836 + 1536 WP_218598050.1 regulatory iron-sulfur-containing complex subunit RicT -
KV700_RS12275 2881814..2882308 + 495 WP_166383529.1 gliding motility lipoprotein GldH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10325.95 Da        Isoelectric Point: 9.9558

>T209458 WP_218598048.1 NZ_CP079195:2878120-2878380 [Polaribacter sp. NJDZ03]
MRLIWSASSWNDYVYWQKVDKKIVKRINELIKSCVRTPFEGIGKPEALKGDLQGYWSRRITSEHRLVYKYENEQLLIAAC
RYHYGK

Download         Length: 261 bp

>T209458 NZ_CP104112:c2748367-2748113 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9511.86 Da        Isoelectric Point: 5.8505

>AT209458 WP_218598047.1 NZ_CP079195:2877871-2878119 [Polaribacter sp. NJDZ03]
METVNYTDFRSNLKHWFDKVFNDVSDIVIKRKGGKDLVLISLDEYNSLKETSYLLTGKNRDVLLNSIKELEAGKGFQKEL
IE

Download         Length: 249 bp

>AT209458 NZ_CP104112:c2748615-2748364 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References