Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2158923..2159139 Replicon chromosome
Accession NZ_CP078521
Organism Staphylococcus aureus strain ATCC 29213

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag KWH15_RS10735 Protein ID WP_001802298.1
Coordinates 2159035..2159139 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2158923..2158978 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KWH15_RS10710 2155072..2155737 - 666 WP_001024095.1 SDR family oxidoreductase -
KWH15_RS10715 2155889..2156209 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
KWH15_RS10720 2156211..2157188 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
KWH15_RS10725 2157454..2158545 + 1092 WP_000495669.1 hypothetical protein -
- 2158923..2158978 + 56 - - Antitoxin
KWH15_RS10735 2159035..2159139 - 105 WP_001802298.1 hypothetical protein Toxin
KWH15_RS10740 2159656..2159826 + 171 WP_001792292.1 transposase -
KWH15_RS10745 2159819..2159977 + 159 WP_001792784.1 hypothetical protein -
KWH15_RS10750 2160635..2161492 - 858 WP_031769139.1 HAD family hydrolase -
KWH15_RS10755 2161560..2162342 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T209208 WP_001802298.1 NZ_CP078521:c2159139-2159035 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T209208 NZ_CP103965:272028-272210 [Pseudomonas sp. N3-W]
ATGCGAAGTCGGGAAATGATCAGGATGATCGAGCACGATGGTTCGTATCTGGTGGCAGTGAAAGGCAGCCACCATCAATA
TAAGCATTCGTTCAAATCAGGCAGGGTGACGATCAAGCACCCTGACTCGGATCTACCCAAAGGGACGATCAACGGCATAT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin


Download         Length: 56 bp

>AT209208 NZ_CP078521:2158923-2158978 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References