Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2484080..2484303 | Replicon | chromosome |
Accession | NZ_CP078162 | ||
Organism | Enterococcus faecalis strain NS2 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | KVY10_RS11715 | Protein ID | WP_256356963.1 |
Coordinates | 2484199..2484303 (-) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2484080..2484225 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KVY10_RS11700 | 2479447..2480160 | - | 714 | WP_002367455.1 | trehalose operon repressor | - |
KVY10_RS11705 | 2480422..2483166 | + | 2745 | WP_218391304.1 | glycosyl hydrolase family 65 protein | - |
KVY10_RS11710 | 2483181..2483831 | + | 651 | WP_218391305.1 | beta-phosphoglucomutase | - |
- | 2484080..2484225 | + | 146 | - | - | Antitoxin |
KVY10_RS11715 | 2484199..2484303 | - | 105 | WP_256356963.1 | putative holin-like toxin | Toxin |
KVY10_RS11720 | 2484817..2485410 | + | 594 | WP_002385181.1 | PBECR4 domain-containing protein | - |
KVY10_RS11725 | 2485650..2485793 | - | 144 | WP_002367458.1 | type I toxin-antitoxin system toxin PepG1 | - |
KVY10_RS13040 | 2486202..2486327 | - | 126 | WP_010821164.1 | hypothetical protein | - |
KVY10_RS11730 | 2486609..2487142 | + | 534 | WP_002385180.1 | CPBP family intramembrane metalloprotease | - |
KVY10_RS11735 | 2487195..2488166 | - | 972 | WP_002381060.1 | ribose-phosphate diphosphokinase | - |
KVY10_RS11740 | 2488341..2488778 | - | 438 | WP_002354871.1 | peptide-methionine (R)-S-oxide reductase MsrB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3799.63 Da Isoelectric Point: 10.0079
>T209156 WP_256356963.1 NZ_CP078162:c2484303-2484199 [Enterococcus faecalis]
MSAYETIQTLLGFGMFTIALIALIVKLLKNDNKK
MSAYETIQTLLGFGMFTIALIALIVKLLKNDNKK
Download Length: 105 bp
>T209156 NZ_CP103864:3062318-3062716 [Escherichia coli O157:H7]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAGCTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACTTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAATCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAGCTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACTTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAATCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
Antitoxin
Download Length: 146 bp
>AT209156 NZ_CP078162:2484080-2484225 [Enterococcus faecalis]
TGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGATT
TTGTTACAAAAAATAACCGTACTCGATCAAAGTAAACGGTTATTTTTTATTGTCATTTTTAAGCAA
TGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGATT
TTGTTACAAAAAATAACCGTACTCGATCAAAGTAAACGGTTATTTTTTATTGTCATTTTTAAGCAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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