209156

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2484080..2484303 Replicon chromosome
Accession NZ_CP078162
Organism Enterococcus faecalis strain NS2

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag KVY10_RS11715 Protein ID WP_256356963.1
Coordinates 2484199..2484303 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2484080..2484225 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KVY10_RS11700 2479447..2480160 - 714 WP_002367455.1 trehalose operon repressor -
KVY10_RS11705 2480422..2483166 + 2745 WP_218391304.1 glycosyl hydrolase family 65 protein -
KVY10_RS11710 2483181..2483831 + 651 WP_218391305.1 beta-phosphoglucomutase -
- 2484080..2484225 + 146 - - Antitoxin
KVY10_RS11715 2484199..2484303 - 105 WP_256356963.1 putative holin-like toxin Toxin
KVY10_RS11720 2484817..2485410 + 594 WP_002385181.1 PBECR4 domain-containing protein -
KVY10_RS11725 2485650..2485793 - 144 WP_002367458.1 type I toxin-antitoxin system toxin PepG1 -
KVY10_RS13040 2486202..2486327 - 126 WP_010821164.1 hypothetical protein -
KVY10_RS11730 2486609..2487142 + 534 WP_002385180.1 CPBP family intramembrane metalloprotease -
KVY10_RS11735 2487195..2488166 - 972 WP_002381060.1 ribose-phosphate diphosphokinase -
KVY10_RS11740 2488341..2488778 - 438 WP_002354871.1 peptide-methionine (R)-S-oxide reductase MsrB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-34)


Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3799.63 Da        Isoelectric Point: 10.0079

>T209156 WP_256356963.1 NZ_CP078162:c2484303-2484199 [Enterococcus faecalis]
MSAYETIQTLLGFGMFTIALIALIVKLLKNDNKK

Download         Length: 105 bp

>T209156 NZ_CP103864:3062318-3062716 [Escherichia coli O157:H7]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAGCTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACTTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAATCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 146 bp

>AT209156 NZ_CP078162:2484080-2484225 [Enterococcus faecalis]
TGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGATT
TTGTTACAAAAAATAACCGTACTCGATCAAAGTAAACGGTTATTTTTTATTGTCATTTTTAAGCAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References