Detailed information of TA system TA209151

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 312154..312349
• Replicon: chromosome
• Accession: NZ_CP078162
• Organism: Enterococcus faecalis strain NS2

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KVY10_RS01570
• Protein ID: WP_122975133.1
• Coordinates: 312254..312349 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	312154..312219 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KVY10_RS01555	307781..309529	+	1749	WP_218391392.1	PTS transporter subunit EIIC	-
KVY10_RS01560	309520..311553	+	2034	WP_002355275.1	BglG family transcription antiterminator	-
KVY10_RS01565	311564..311998	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	312154..312219	+	66	-	-	Antitoxin
KVY10_RS01570	312254..312349	-	96	WP_122975133.1	type I toxin-antitoxin system Fst family toxin	Toxin
KVY10_RS01575	312595..314367	+	1773	WP_002405272.1	PTS mannitol-specific transporter subunit IIBC	-
KVY10_RS01580	314382..314819	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
KVY10_RS01585	314834..315988	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
KVY10_RS01590	316055..317170	-	1116	WP_174083960.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3645.44 Da
• Isoelectric Point: 4.5869

>T209151 WP_122975133.1 NZ_CP078162:c312349-312254 [Enterococcus faecalis]
MYDIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T209151 NZ_CP103864:c1754659-1754552 [Escherichia coli O157:H7]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 66 bp

>AT209151 NZ_CP078162:312154-312219 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin