Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/-
Location 312154..312349 Replicon chromosome
Accession NZ_CP078162
Organism Enterococcus faecalis strain NS2

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag KVY10_RS01570 Protein ID WP_122975133.1
Coordinates 312254..312349 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 312154..312219 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KVY10_RS01555 307781..309529 + 1749 WP_218391392.1 PTS transporter subunit EIIC -
KVY10_RS01560 309520..311553 + 2034 WP_002355275.1 BglG family transcription antiterminator -
KVY10_RS01565 311564..311998 + 435 WP_002358391.1 PTS sugar transporter subunit IIA -
- 312154..312219 + 66 - - Antitoxin
KVY10_RS01570 312254..312349 - 96 WP_122975133.1 type I toxin-antitoxin system Fst family toxin Toxin
KVY10_RS01575 312595..314367 + 1773 WP_002405272.1 PTS mannitol-specific transporter subunit IIBC -
KVY10_RS01580 314382..314819 + 438 WP_002355279.1 PTS sugar transporter subunit IIA -
KVY10_RS01585 314834..315988 + 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
KVY10_RS01590 316055..317170 - 1116 WP_174083960.1 FAD-dependent oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-35)


Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3645.44 Da        Isoelectric Point: 4.5869

>T209151 WP_122975133.1 NZ_CP078162:c312349-312254 [Enterococcus faecalis]
MYDIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T209151 NZ_CP103864:c1754659-1754552 [Escherichia coli O157:H7]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 66 bp

>AT209151 NZ_CP078162:312154-312219 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References