Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 809039..809585 Replicon chromosome
Accession NZ_CP078066
Organism Bradyrhizobium arachidis strain Hy4

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KUL72_RS03880 Protein ID WP_258764867.1
Coordinates 809376..809585 (-) Length 70 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KUL72_RS03875 Protein ID WP_194479308.1
Coordinates 809039..809320 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KUL72_RS03850 (KUL72_03825) 804353..804487 - 135 WP_008542748.1 50S ribosomal protein L34 -
KUL72_RS03855 (KUL72_03830) 804848..806377 + 1530 WP_258764864.1 HAMP domain-containing sensor histidine kinase -
KUL72_RS03865 (KUL72_03840) 806696..807637 - 942 WP_258764865.1 sensor domain-containing diguanylate cyclase -
KUL72_RS03870 (KUL72_03845) 807768..808865 - 1098 WP_258764866.1 glycoside hydrolase family 3 N-terminal domain-containing protein -
KUL72_RS03875 (KUL72_03850) 809039..809320 - 282 WP_194479308.1 helix-turn-helix transcriptional regulator Antitoxin
KUL72_RS03880 (KUL72_03855) 809376..809585 - 210 WP_258764867.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KUL72_RS03885 (KUL72_03860) 809788..811083 - 1296 WP_258764868.1 MFS transporter -
KUL72_RS03890 (KUL72_03865) 811172..811768 + 597 WP_194479311.1 TetR/AcrR family transcriptional regulator -
KUL72_RS03895 (KUL72_03870) 811846..812487 + 642 WP_258764869.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(3-65)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-83)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 7785.19 Da        Isoelectric Point: 11.2197

>T208956 WP_258764867.1 NZ_CP078066:c809585-809376 [Bradyrhizobium arachidis]
MESLGEPHVKHLEGKLWELRLTGRDGIARALYVTAIGRRVVVVRALVKKTQKTPRAEIELALRRANEIA

Download         Length: 210 bp

>T208956 NZ_CP103762:2878730-2878837 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10197.84 Da        Isoelectric Point: 10.8350

>AT208956 WP_194479308.1 NZ_CP078066:c809320-809039 [Bradyrhizobium arachidis]
MTIPFDKLKARLLANPKVKAEYDALAPEFEIAAELLRARLRAGFSQSELAVRMGTSQSTIARLESGQTLPSTKTLLRYAE
ATGSKFRVRLSAA

Download         Length: 282 bp

>AT208956 NZ_CP103762:c2878677-2878616 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References