Detailed information of TA system TA208713

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1908900..1909080
• Replicon: chromosome
• Accession: NZ_CP077936
• Organism: Staphylococcus aureus strain 319

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KU496_RS09215
• Protein ID: WP_001801861.1
• Coordinates: 1908900..1908995 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1909023..1909080 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KU496_RS09185	1904044..1904670	+	627	WP_000669038.1	hypothetical protein	-
KU496_RS09190	1904711..1905055	+	345	WP_000627550.1	DUF3969 family protein	-
KU496_RS09195	1905153..1905725	+	573	WP_000414222.1	hypothetical protein	-
KU496_RS09200	1905874..1907241	-	1368	WP_001093574.1	FRG domain-containing protein	-
KU496_RS09205	1907241..1907810	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
KU496_RS09210	1908003..1908449	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
KU496_RS09215	1908900..1908995	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1909023..1909080	-	58	-	-	Antitoxin
KU496_RS09220	1909118..1909219	+	102	WP_001791232.1	hypothetical protein	-
KU496_RS09225	1909394..1909837	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
KU496_RS09230	1909837..1910280	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
KU496_RS09235	1910280..1910722	-	443	Protein_1824	DUF1433 domain-containing protein	-
KU496_RS09240	1911247..1913667	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T208713 WP_001801861.1 NZ_CP077936:1908900-1908995 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T208713 NZ_CP103714:834138-834548 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGACGGATCCATGCCCGTCGCGGGGAAATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT208713 NZ_CP077936:c1909080-1909023 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin