Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1565049..1565231 Replicon chromosome
Accession NZ_CP077933
Organism Staphylococcus aureus strain 359

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KU512_RS07840 Protein ID WP_001801861.1
Coordinates 1565049..1565144 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1565172..1565231 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU512_RS07800 1560708..1561334 + 627 WP_000669046.1 hypothetical protein -
KU512_RS07805 1561375..1561719 + 345 WP_000627551.1 DUF3969 family protein -
KU512_RS07810 1561817..1562368 + 552 WP_000414205.1 hypothetical protein -
KU512_RS07815 1562586..1563227 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
KU512_RS07820 1563342..1563527 - 186 WP_000809857.1 hypothetical protein -
KU512_RS07825 1563529..1563705 - 177 WP_000375476.1 hypothetical protein -
KU512_RS07830 1563716..1564099 - 384 WP_000070812.1 hypothetical protein -
KU512_RS07835 1564703..1564846 - 144 WP_001549059.1 transposase -
KU512_RS07840 1565049..1565144 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1565172..1565231 - 60 - - Antitoxin
KU512_RS07845 1565267..1565368 + 102 WP_001791893.1 hypothetical protein -
KU512_RS07850 1565346..1565522 - 177 Protein_1544 transposase -
KU512_RS07855 1565716..1566093 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T208696 WP_001801861.1 NZ_CP077933:1565049-1565144 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T208696 NZ_CP103710:2074889-2074991 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 60 bp

>AT208696 NZ_CP077933:c1565231-1565172 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References