Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 225008..225192 Replicon chromosome
Accession NZ_CP077924
Organism Staphylococcus aureus strain 200

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag KU536_RS01115 Protein ID WP_000482647.1
Coordinates 225008..225115 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 225132..225192 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU536_RS01090 220365..220838 + 474 WP_000456489.1 GyrI-like domain-containing protein -
KU536_RS01095 220961..222172 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
KU536_RS01100 222360..223019 - 660 WP_000831300.1 hypothetical protein -
KU536_RS01105 223079..224221 - 1143 WP_001176859.1 glycerate kinase -
KU536_RS01110 224488..224874 + 387 WP_000779355.1 flippase GtxA -
KU536_RS01115 225008..225115 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 225132..225192 - 61 - - Antitoxin
KU536_RS01120 225819..227582 + 1764 WP_001064818.1 ABC transporter ATP-binding protein -
KU536_RS01125 227607..229340 + 1734 WP_000486511.1 ABC transporter ATP-binding protein -
KU536_RS01130 229571..229738 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T208627 WP_000482647.1 NZ_CP077924:225008-225115 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T208627 NZ_CP103694:1987170-1987273 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 61 bp

>AT208627 NZ_CP077924:c225192-225132 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References