Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprG-sprF/- |
| Location | 1378079..1378305 | Replicon | chromosome |
| Accession | NZ_CP077922 | ||
| Organism | Staphylococcus aureus strain 202 | ||
Toxin (Protein)
| Gene name | SprG2 | Uniprot ID | A0A0E0VS87 |
| Locus tag | KU538_RS06790 | Protein ID | WP_000253688.1 |
| Coordinates | 1378198..1378305 (-) | Length | 36 a.a. |
Antitoxin (RNA)
| Gene name | SprF3 | ||
| Locus tag | - | ||
| Coordinates | 1378079..1378145 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KU538_RS06750 (1373280) | 1373280..1373477 | + | 198 | WP_000239614.1 | phospholipase | - |
| KU538_RS06755 (1373849) | 1373849..1374028 | + | 180 | WP_000669789.1 | hypothetical protein | - |
| KU538_RS06760 (1374339) | 1374339..1374599 | + | 261 | WP_001791826.1 | hypothetical protein | - |
| KU538_RS06765 (1374652) | 1374652..1375002 | - | 351 | WP_000702263.1 | complement inhibitor SCIN-A | - |
| KU538_RS06770 (1375687) | 1375687..1376136 | + | 450 | WP_000727649.1 | chemotaxis-inhibiting protein CHIPS | - |
| KU538_RS06775 (1376231) | 1376231..1377685 | - | 1455 | WP_000930259.1 | N-acetylmuramoyl-L-alanine amidase | - |
| KU538_RS06780 (1377697) | 1377697..1377999 | - | 303 | WP_000387656.1 | phage holin | - |
| - (1378079) | 1378079..1378145 | + | 67 | NuclAT_0 | - | Antitoxin |
| - (1378079) | 1378079..1378145 | + | 67 | NuclAT_0 | - | Antitoxin |
| - (1378079) | 1378079..1378145 | + | 67 | NuclAT_0 | - | Antitoxin |
| - (1378079) | 1378079..1378145 | + | 67 | NuclAT_0 | - | Antitoxin |
| KU538_RS06785 (1378050) | 1378050..1378154 | + | 105 | Protein_1311 | hypothetical protein | - |
| KU538_RS06790 (1378198) | 1378198..1378305 | - | 108 | WP_000253688.1 | putative holin-like toxin | Toxin |
| KU538_RS06795 (1378537) | 1378537..1378833 | - | 297 | WP_000539688.1 | DUF2951 domain-containing protein | - |
| KU538_RS06800 (1378891) | 1378891..1379178 | - | 288 | WP_001040257.1 | hypothetical protein | - |
| KU538_RS06805 (1379225) | 1379225..1379377 | - | 153 | WP_001181555.1 | hypothetical protein | - |
| KU538_RS06810 (1379364) | 1379364..1383044 | - | 3681 | WP_000582140.1 | phage tail spike protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | scn / chp / hlb / groEL | 1374652..1425622 | 50970 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3817.78 Da Isoelectric Point: 10.4997
>T208601 WP_000253688.1 NZ_CP077922:c1378305-1378198 [Staphylococcus aureus]
VVSIVDALNLMFSFGMFIVTLLGLVIAIVKLSHKK
VVSIVDALNLMFSFGMFIVTLLGLVIAIVKLSHKK
Download Length: 108 bp
>T208601 NZ_CP103683:c4549760-4549575 [Enterobacter hormaechei]
GTGAAAAGTGCGGATATCATTGCTGTTCTGGTTAGCCATGGCTGGAAATGTGTAAGAACGAAGGGAAGCCATCATCAGTT
TCGCCATCCAGTGCAAAAAGGGTTGGTAACCGTTCCGCATCCTAAAAAGGACATTAAACCGGGCACTCTCGCACAGATCT
GGCGACAGGCGGGCATTAAACACTGA
GTGAAAAGTGCGGATATCATTGCTGTTCTGGTTAGCCATGGCTGGAAATGTGTAAGAACGAAGGGAAGCCATCATCAGTT
TCGCCATCCAGTGCAAAAAGGGTTGGTAACCGTTCCGCATCCTAAAAAGGACATTAAACCGGGCACTCTCGCACAGATCT
GGCGACAGGCGGGCATTAAACACTGA
Antitoxin
Download Length: 67 bp
>AT208601 NZ_CP077922:1378079-1378145 [Staphylococcus aureus]
ATAAATAGAAAAAGGGCAACATGCGGAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCT
ATAAATAGAAAAAGGGCAACATGCGGAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
