Detailed information of TA system TA208513

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2328542..2328758
• Replicon: chromosome
• Accession: NZ_CP077911
• Organism: Staphylococcus aureus strain 318

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: KU501_RS11695
• Protein ID: WP_073392962.1
• Coordinates: 2328654..2328758 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2328542..2328597 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KU501_RS11670	2323635..2323955	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
KU501_RS11675	2323957..2324937	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
KU501_RS11680	2325203..2326294	+	1092	WP_000495684.1	hypothetical protein	-
KU501_RS11685	2326582..2328228	+	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2328542..2328597	+	56	-	-	Antitoxin
KU501_RS11695	2328654..2328758	-	105	WP_073392962.1	hypothetical protein	Toxin
KU501_RS11700	2329438..2329596	+	159	WP_001792784.1	hypothetical protein	-
KU501_RS11705	2330255..2331112	-	858	WP_000370937.1	HAD family hydrolase	-
KU501_RS11710	2331180..2331962	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2326582..2328228	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T208513 WP_073392962.1 NZ_CP077911:c2328758-2328654 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T208513 NZ_CP103672:955097-955504 [Escherichia coli O25b:H4-ST131]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATTCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT208513 NZ_CP077911:2328542-2328597 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin