Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 1582110..1582294 | Replicon | chromosome |
Accession | NZ_CP077908 | ||
Organism | Staphylococcus aureus strain 322 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | A0A2P7CQJ7 |
Locus tag | KU527_RS08015 | Protein ID | WP_000482647.1 |
Coordinates | 1582187..1582294 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 1582110..1582170 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KU527_RS07995 | 1577696..1577863 | - | 168 | WP_031785511.1 | hypothetical protein | - |
KU527_RS08000 | 1578094..1579827 | - | 1734 | WP_000488492.1 | ABC transporter ATP-binding protein | - |
KU527_RS08005 | 1579876..1581615 | - | 1740 | WP_001064831.1 | ABC transporter ATP-binding protein | - |
KU527_RS08010 | 1581993..1582160 | - | 168 | WP_000301894.1 | hypothetical protein | - |
- | 1582110..1582170 | + | 61 | - | - | Antitoxin |
KU527_RS08015 | 1582187..1582294 | - | 108 | WP_000482647.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
KU527_RS08020 | 1582428..1582814 | - | 387 | WP_000779354.1 | flippase GtxA | - |
KU527_RS08025 | 1583082..1584224 | + | 1143 | WP_001176860.1 | glycerate kinase | - |
KU527_RS08030 | 1584284..1584943 | + | 660 | WP_000831298.1 | membrane protein | - |
KU527_RS08035 | 1585123..1586334 | + | 1212 | WP_001191975.1 | multidrug effflux MFS transporter | - |
KU527_RS08040 | 1586457..1586930 | - | 474 | WP_000456491.1 | GyrI-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4012.76 Da Isoelectric Point: 10.4935
>T208497 WP_000482647.1 NZ_CP077908:c1582294-1582187 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T208497 NZ_CP103657:c4438524-4438174 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA
Antitoxin
Download Length: 61 bp
>AT208497 NZ_CP077908:1582110-1582170 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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