Detailed information of TA system TA208483

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1970615..1970795
• Replicon: chromosome
• Accession: NZ_CP077899
• Organism: Staphylococcus aureus strain 324

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KU505_RS09390
• Protein ID: WP_001801861.1
• Coordinates: 1970615..1970710 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1970738..1970795 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KU505_RS09350	1965652..1966278	+	627	WP_000669033.1	hypothetical protein	-
KU505_RS09355	1966319..1966660	+	342	WP_060649610.1	DUF3969 family protein	-
KU505_RS09360	1966761..1967333	+	573	WP_000414203.1	hypothetical protein	-
KU505_RS09365	1967531..1968159	-	629	Protein_1847	ImmA/IrrE family metallo-endopeptidase	-
KU505_RS09370	1968273..1968458	-	186	WP_000809681.1	hypothetical protein	-
KU505_RS09375	1968460..1968636	-	177	WP_000375476.1	hypothetical protein	-
KU505_RS09380	1968647..1969030	-	384	WP_025174588.1	hypothetical protein	-
KU505_RS09385	1969717..1970163	-	447	WP_000747807.1	DUF1433 domain-containing protein	-
KU505_RS09390	1970615..1970710	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1970738..1970795	-	58	-	-	Antitoxin
KU505_RS09395	1970833..1970931	+	99	Protein_1853	hypothetical protein	-
KU505_RS09400	1970927..1971094	+	168	WP_001268925.1	hypothetical protein	-
KU505_RS09405	1971720..1972163	-	444	WP_000731441.1	DUF1433 domain-containing protein	-
KU505_RS09410	1972163..1972625	-	463	Protein_1856	DUF1433 domain-containing protein	-
KU505_RS09415	1972625..1973050	-	426	WP_000260278.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T208483 WP_001801861.1 NZ_CP077899:1970615-1970710 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T208483 NZ_CP103657:1169471-1169806 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATACGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTCTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT208483 NZ_CP077899:c1970795-1970738 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin