Detailed information of TA system TA208479

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1010733..1010959
• Replicon: chromosome
• Accession: NZ_CP077899
• Organism: Staphylococcus aureus strain 324

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: KU505_RS04860
• Protein ID: WP_044122766.1
• Coordinates: 1010733..1010837 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1010866..1010959 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KU505_RS04845 (1006970)	1006970..1007344	+	375	WP_000343402.1	hypothetical protein	-
KU505_RS04850 (1007469)	1007469..1009355	+	1887	WP_001207581.1	glucosaminidase domain-containing protein	-
KU505_RS04855 (1009798)	1009798..1010571	+	774	WP_000750404.1	staphylococcal enterotoxin type A	-
KU505_RS04860 (1010733)	1010733..1010837	+	105	WP_044122766.1	hypothetical protein	Toxin
- (1010866)	1010866..1010959	-	94	NuclAT_1	-	Antitoxin
- (1010866)	1010866..1010959	-	94	NuclAT_1	-	Antitoxin
- (1010866)	1010866..1010959	-	94	NuclAT_1	-	Antitoxin
- (1010866)	1010866..1010959	-	94	NuclAT_1	-	Antitoxin
KU505_RS04865 (1010893)	1010893..1010988	-	96	Protein_950	hypothetical protein	-
KU505_RS04870 (1011040)	1011040..1011294	+	255	WP_000611512.1	phage holin	-
KU505_RS04875 (1011306)	1011306..1012061	+	756	WP_000861038.1	CHAP domain-containing protein	-
KU505_RS04880 (1012287)	1012287..1012415	+	129	WP_000884149.1	hypothetical protein	-
KU505_RS04885 (1012487)	1012487..1012597	+	111	WP_000139425.1	hypothetical protein	-
KU505_RS04890 (1012599)	1012599..1012784	+	186	WP_001286805.1	hypothetical protein	-
KU505_RS04895 (1013215)	1013215..1013394	+	180	WP_000201921.1	hypothetical protein	-
KU505_RS04900 (1013416)	1013416..1013943	+	528	WP_000455171.1	DUF4065 domain-containing protein	-
KU505_RS04905 (1013933)	1013933..1014331	+	399	WP_000557463.1	hypothetical protein	-
KU505_RS04910 (1014776)	1014776..1014915	+	140	Protein_959	hypothetical protein	-
KU505_RS04915 (1014921)	1014921..1015235	-	315	WP_000274031.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sea	971622..1014331	42709

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3932.77 Da
• Isoelectric Point: 5.5724

>T208479 WP_044122766.1 NZ_CP077899:1010733-1010837 [Staphylococcus aureus]
MLLLERNSMSDFEMLMVVLTIIGLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T208479 NZ_CP103657:224687-224794 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 94 bp

>AT208479 NZ_CP077899:c1010959-1010866 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGGCTTTTCATAGAAAAA
TTATAAAAATAACC

Structures

Antitoxin