Detailed information of TA system TA208455

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2398407..2398633
• Replicon: chromosome
• Accession: NZ_CP077894
• Organism: Staphylococcus aureus strain 329

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: KU540_RS11880
• Protein ID: WP_044122766.1
• Coordinates: 2398529..2398633 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2398407..2398500 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KU540_RS11825 (2394131)	2394131..2394445	+	315	WP_000274031.1	hypothetical protein	-
KU540_RS11830 (2394451)	2394451..2394590	-	140	Protein_2291	hypothetical protein	-
KU540_RS11835 (2395035)	2395035..2395433	-	399	WP_000557463.1	hypothetical protein	-
KU540_RS11840 (2395423)	2395423..2395950	-	528	WP_000455171.1	DUF4065 domain-containing protein	-
KU540_RS11845 (2395972)	2395972..2396151	-	180	WP_000201921.1	hypothetical protein	-
KU540_RS11850 (2396582)	2396582..2396767	-	186	WP_001286805.1	hypothetical protein	-
KU540_RS11855 (2396769)	2396769..2396879	-	111	WP_000139425.1	hypothetical protein	-
KU540_RS11860 (2396951)	2396951..2397079	-	129	WP_000884149.1	hypothetical protein	-
KU540_RS11865 (2397305)	2397305..2398060	-	756	WP_000861038.1	CHAP domain-containing protein	-
KU540_RS11870 (2398072)	2398072..2398326	-	255	WP_000611512.1	phage holin	-
KU540_RS11875 (2398378)	2398378..2398473	+	96	Protein_2300	hypothetical protein	-
- (2398407)	2398407..2398500	+	94	NuclAT_1	-	Antitoxin
- (2398407)	2398407..2398500	+	94	NuclAT_1	-	Antitoxin
- (2398407)	2398407..2398500	+	94	NuclAT_1	-	Antitoxin
- (2398407)	2398407..2398500	+	94	NuclAT_1	-	Antitoxin
KU540_RS11880 (2398529)	2398529..2398633	-	105	WP_044122766.1	hypothetical protein	Toxin
KU540_RS11885 (2398795)	2398795..2399568	-	774	WP_000750404.1	staphylococcal enterotoxin type A	-
KU540_RS11890 (2400011)	2400011..2401897	-	1887	WP_001207581.1	glucosaminidase domain-containing protein	-
KU540_RS11895 (2402022)	2402022..2402396	-	375	WP_000343402.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sea	2395035..2437744	42709

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3932.77 Da
• Isoelectric Point: 5.5724

>T208455 WP_044122766.1 NZ_CP077894:c2398633-2398529 [Staphylococcus aureus]
MLLLERNSMSDFEMLMVVLTIIGLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T208455 NZ_CP103645:c4269181-4268831 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin

Nucleotide

• Length: 94 bp

>AT208455 NZ_CP077894:2398407-2398500 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGGCTTTTCATAGAAAAA
TTATAAAAATAACC

Structures

Antitoxin