Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 800055..800239 Replicon chromosome
Accession NZ_CP077894
Organism Staphylococcus aureus strain 329

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag KU540_RS03750 Protein ID WP_000482647.1
Coordinates 800055..800162 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 800179..800239 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU540_RS03725 795419..795892 + 474 WP_000456490.1 GyrI-like domain-containing protein -
KU540_RS03730 796015..797226 - 1212 WP_001191973.1 multidrug effflux MFS transporter -
KU540_RS03735 797406..798065 - 660 WP_000831298.1 membrane protein -
KU540_RS03740 798125..799267 - 1143 WP_001176872.1 glycerate kinase -
KU540_RS03745 799535..799921 + 387 WP_000779354.1 flippase GtxA -
KU540_RS03750 800055..800162 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 800179..800239 - 61 - - Antitoxin
KU540_RS03755 800734..802473 + 1740 WP_001064832.1 ABC transporter ATP-binding protein -
KU540_RS03760 802522..804255 + 1734 WP_000488492.1 ABC transporter ATP-binding protein -
KU540_RS03765 804486..804653 + 168 WP_031785511.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T208444 WP_000482647.1 NZ_CP077894:800055-800162 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T208444 NZ_CP103645:2076616-2076719 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 61 bp

>AT208444 NZ_CP077894:c800239-800179 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References