Detailed information of TA system TA208441

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 774635..774817
• Replicon: chromosome
• Accession: NZ_CP077893
• Organism: Staphylococcus aureus strain 332

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KU542_RS04200
• Protein ID: WP_001801861.1
• Coordinates: 774722..774817 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	774635..774694 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KU542_RS04185	773773..774150	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
KU542_RS04190	774344..774520	+	177	Protein_786	transposase	-
KU542_RS04195	774498..774599	-	102	WP_001791893.1	hypothetical protein	-
-	774635..774694	+	60	-	-	Antitoxin
KU542_RS04200	774722..774817	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
KU542_RS04205	775020..775163	+	144	WP_001549059.1	transposase	-
KU542_RS04210	775767..776150	+	384	WP_000070811.1	hypothetical protein	-
KU542_RS04215	776161..776337	+	177	WP_000375476.1	hypothetical protein	-
KU542_RS04220	776339..776524	+	186	WP_000809857.1	hypothetical protein	-
KU542_RS04225	776638..777279	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
KU542_RS04230	777497..778048	-	552	WP_000414205.1	hypothetical protein	-
KU542_RS04235	778146..778490	-	345	WP_000627551.1	DUF3969 family protein	-
KU542_RS04240	778531..779157	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	741545..812257	70712

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T208441 WP_001801861.1 NZ_CP077893:c774817-774722 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T208441 NZ_CP103645:1846257-1846508 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT208441 NZ_CP077893:774635-774694 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin