Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2554005..2554222 Replicon chromosome
Accession NZ_CP077889
Organism Staphylococcus aureus strain 333

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag KU539_RS12595 Protein ID WP_001802298.1
Coordinates 2554118..2554222 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2554005..2554060 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU539_RS12570 2550142..2550807 - 666 WP_001024094.1 SDR family oxidoreductase -
KU539_RS12575 2550959..2551279 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
KU539_RS12580 2551281..2552261 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
KU539_RS12585 2552527..2553618 + 1092 WP_000495671.1 lytic regulatory protein -
- 2554005..2554060 + 56 - - Antitoxin
KU539_RS12595 2554118..2554222 - 105 WP_001802298.1 hypothetical protein Toxin
KU539_RS12600 2554383..2554866 - 484 Protein_2448 recombinase family protein -
KU539_RS12605 2554909..2556045 - 1137 WP_000115564.1 SAP domain-containing protein -
KU539_RS12610 2556334..2556426 + 93 WP_001790138.1 hypothetical protein -
KU539_RS12615 2556715..2556899 + 185 Protein_2451 exotoxin -
KU539_RS12620 2557131..2557988 - 858 WP_000370924.1 HAD family hydrolase -
KU539_RS12625 2558056..2558838 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T208422 WP_001802298.1 NZ_CP077889:c2554222-2554118 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T208422 NZ_CP103639:4045055-4045273 [Klebsiella aerogenes]
ATGTCTGGTAAACCATTAACTAAAACAGACTATTTGATGCGTTTACGCCGCTGTCAGACAATTGATACGCTGGAGCGCGT
AATTGAAAAGAATAAATATGAACTTTCCGACAATGAATTGGCGGTATTTTACTCAGCAGCCGACCATCGTCTTGCTGAAT
TGACCATGAATAAGCTATACGACAAAATCCCAACTTCAGTATGGAAATTTATCCGCTAG

Antitoxin


Download         Length: 56 bp

>AT208422 NZ_CP077889:2554005-2554060 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References