Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 250100..250316 Replicon chromosome
Accession NZ_CP077854
Organism Staphylococcus aureus strain N4

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag KU508_RS01420 Protein ID WP_001802298.1
Coordinates 250212..250316 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 250100..250155 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU508_RS01395 246306..246971 - 666 WP_001024095.1 SDR family oxidoreductase -
KU508_RS01400 247123..247443 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
KU508_RS01405 247445..248422 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
KU508_RS01410 248688..249779 + 1092 WP_000495669.1 hypothetical protein -
- 250100..250155 + 56 - - Antitoxin
KU508_RS01420 250212..250316 - 105 WP_001802298.1 hypothetical protein Toxin
KU508_RS01425 250996..251154 + 159 WP_001792784.1 hypothetical protein -
KU508_RS01430 251812..252669 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
KU508_RS01435 252737..253519 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T208120 WP_001802298.1 NZ_CP077854:c250316-250212 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T208120 NZ_CP103570:c4234715-4234542 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 56 bp

>AT208120 NZ_CP077854:250100-250155 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References