Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) hok-sok/-
Location 785369..785627 Replicon chromosome
Accession NZ_CP077850
Organism Erwinia amylovora strain CP200242 isolate missinsg

Toxin (Protein)


Gene name hok Uniprot ID -
Locus tag KTR61_RS03420 Protein ID WP_231840709.1
Coordinates 785529..785627 (+) Length 33 a.a.

Antitoxin (RNA)


Gene name sok
Locus tag -
Coordinates 785369..785415 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KTR61_RS03380 (KTR61_03350) 780815..780958 - 144 WP_004160049.1 hypothetical protein -
KTR61_RS03385 (KTR61_03355) 781431..781823 - 393 WP_004160048.1 DoxX family protein -
KTR61_RS03390 (KTR61_03360) 782033..782314 - 282 WP_004160039.1 YqjK-like family protein -
KTR61_RS03395 (KTR61_03365) 782314..782706 - 393 WP_004160038.1 phage holin family protein -
KTR61_RS03400 (KTR61_03370) 782708..783013 - 306 WP_004160037.1 DUF883 family protein -
KTR61_RS03405 (KTR61_03375) 783056..783427 - 372 WP_004160036.1 DUF1090 domain-containing protein -
KTR61_RS03410 (KTR61_03380) 783595..783987 - 393 WP_004160035.1 EnvZ/OmpR regulon moderator MzrA -
KTR61_RS03415 (KTR61_03385) 783984..784658 - 675 WP_004160034.1 DedA family protein -
- 785369..785415 - 47 - - Antitoxin
KTR61_RS03420 785529..785627 + 99 WP_231840709.1 Hok/Gef family protein Toxin
KTR61_RS03425 (KTR61_03395) 785771..787003 - 1233 WP_004160030.1 serine/threonine transporter SstT -
KTR61_RS03430 (KTR61_03400) 787238..788218 - 981 WP_013035818.1 TerC family protein -
KTR61_RS03435 (KTR61_03405) 788631..790322 + 1692 WP_004160025.1 chloride channel protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-28)


Sequences


Toxin        


Download         Length: 33 a.a.        Molecular weight: 3810.40 Da        Isoelectric Point: 8.9407

>T208070 WP_231840709.1 NZ_CP077850:785529-785627 [Erwinia amylovora]
IFTYLTRKSLCEIRYKDGYREVAAFMAYESGK

Download         Length: 99 bp

>T208070 NZ_CP103562:2249247-2249349 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 47 bp

>AT208070 NZ_CP077850:c785415-785369 [Erwinia amylovora]
GCATGCAGATGGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References